NLRP3

NLRP3 Related Products (34):

By Type:	Pan (3) Selective (8)
By Effects:	Inhibitors (28) Agonist (1) Activators (5)

Cat. No.	Product Name	Effect	Purity

HY-100381

Nigericin sodium salt	Activator	≥98.0%
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H⁺, K⁺, and Pb²⁺ ionophore, a NLRP3 activator.

HY-116084

Trimethylamine N-oxide	Activator	≥98.0%
Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients.

HY-101092

QS-21	Activator
QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant.

HY-B0116

Stavudine	Inhibitor	99.67%
Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI).

HY-N0633

Muscone	Inhibitor	≥98.0%
Muscone is the main active monomer of traditional Chinese medicine musk.

HY-150206

NLRP3-IN-13	Inhibitor
NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC₅₀: 2.1 μM).

HY-N10312

Yadanzigan	Inhibitor
Yadanzigan (YDZG) is an anti-inflammatory agent and a NLRP3 inhibitor.

HY-149123

NLRP3-IN-16	Inhibitor
NLRP3-IN-16 is a potent and selective NLRP3 inflammasome inhibitor.

HY-N0373

Licochalcone B	Inhibitor	99.93%
Licochalcone B is an extract from the root of Glycyrrhiza uralensis.

HY-137245A

Emlenoflast sodium	Inhibitor	98.76%
Emlenoflast (MCC7840) sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC₅₀ of <100 nM.

HY-N0496

Ruscogenin	Inhibitor	≥98.0%
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities.

HY-16059

Arglabin	Inhibitor	99.87%
Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor.

HY-139396

BMS-986299	Agonist	99.95%
BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC₅₀ of 1.28 μM.

HY-N2485

4'-Methoxyresveratrol	Activator	99.70%
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a polyphenol derived from Dipterocarpaceae, with antiandrogenic, antifungal and anti-inflammatory activities.

HY-130252

YQ128	Inhibitor	99.83%
YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC₅₀ of 0.30 µM.

HY-100581

CORM-3	Inhibitor
CORM-3, a carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels.

HY-144226

NLRP3/AIM2-IN-3	Inhibitor	98.00%
NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with differential species specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.

HY-122920

Soyasaponin II	Inhibitor	99.81%
Soyasaponin II is a saponin with antiviral activity.

HY-131040

NLRP3-IN-NBC6	Inhibitor	99.40%
NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor (IC₅₀= 574 nM) that acts independently of Ca²⁺.

HY-121988

INF4E	Inhibitor	99.38%
INF4E is a potent NLRP3 inflammasome inhibitor.

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