1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. PPAR
  4. PPARγ Isoform

PPARγ

 
Cat. No. Product Name Effect Purity
  • HY-14649
    Retinoic acid
    Agonist 99.74%
    Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis.
  • HY-17386
    Rosiglitazone
    Agonist 99.90%
    Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM).
  • HY-16578
    GW9662
    Antagonist 99.87%
    GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
  • HY-13956
    Pioglitazone
    Activator 99.66%
    Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
  • HY-13202
    T0070907
    Antagonist 99.98%
    T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.
  • HY-117727A
    Leriglitazone hydrochloride
    Agonist 99.58%
    Leriglitazone (Hydroxypioglitazone) hydrochloride, a metabolite of pioglitazone.
  • HY-17386B
    Rosiglitazone potassium
    Agonist
    Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM).
  • HY-13956B
    Pioglitazone potassium
    Agonist
    Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively.
  • HY-16995
    Pirinixic acid
    Agonist 99.80%
    Pirinixic acid (Wy-14643) is a potent agonist of PPARα, with EC50s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα, PPARγ and PPARδ, respectively.
  • HY-50935
    Troglitazone
    Agonist 98.60%
    Troglitazone is a PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively.
  • HY-15027
    5-Aminosalicylic Acid
    Agonist ≥98.0%
    5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.
  • HY-N0019
    Daidzein
    Activator 99.89%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
  • HY-B2163
    Astaxanthin
    Activator ≥98.0%
    Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant.
  • HY-104049
    Lanifibranor
    Agonist 99.56%
    Lanifibranor is a pan peroxisome proliferator-activated receptor (PPAR) agonist with EC50s of 1.5, 0.87 and 0.21 μM for human PPARα, PPARσ and PPARγ, respectively.
  • HY-13928
    GW0742
    Agonist 99.95%
    GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.
  • HY-13861
    GW7647
    Agonist 98.22%
    GW7647 is a potent PPARα agonist, with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively.
  • HY-15655
    GW1929
    Agonist 99.87%
    GW1929 is a potent PPAR-γ agonist, with a pKi of 8.84 for human PPAR-γ, and pEC50s of 8.56 and 8.27 for human PPAR-γ and murine PPAR-γ, respectively.
  • HY-B0637
    Bezafibrate
    Agonist 99.43%
    Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.
  • HY-15725
    CDDO-Im
    Activator 98.19%
    CDDO-Im (RTA-403) is an activator of Nrf2 and PPAR, with Kis of 232 and 344 nM for PPARα and PPARγ.
  • HY-B0205
    Candesartan
    Agonist 98.50%
    Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist.
Cat. No. Product Name / Synonyms Species Source