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Astaxanthin

19 Cited Publications
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Based on 19 publication(s) in Google Scholar

Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed.

For research use only. We do not sell to patients.

  • Purity: 98.0%
  • CAS No.: 472-61-7
  • Formula: C40H52O4
  • Molecular Weight:596.84
  • Storage:

    -20°C, protect from light, stored under nitrogen

    * The compound is unstable in solutions, freshly prepared is recommended.

  • Astaxanthin Chemical Structure
    Astaxanthin Chemical Structure
  • Experimental Validation Results for Astaxanthin
  • Experimental Validation Results for Astaxanthin
  • Experimental Validation Results for Astaxanthin
  • Experimental Validation Results for Astaxanthin
  • Experimental Validation Results for Astaxanthin
  • Experimental Validation Results for Astaxanthin
  • Experimental Validation Results for Astaxanthin
CAS No.: 472-61-7
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  • Astaxanthin Chemical Structure
    Astaxanthin Chemical Structure
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    Astaxanthin purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Dec 8:501:140750. [Abstract]

    Customer Validation
     Typical DHE fluorescence in zebrafish larvae exposed to PFOS and treated with vitamin C, vitamin E, and Astaxanthin. The results showed that Astaxanthin (AX, 1% w/w in fodder; 0.1 mg/larva/day and 10 mg/adult/day for 4 weeks), when supplemented to the fodder as an antioxidant, scavenged the overload of superoxide induced by PFOS in the liver.

  • 1/16

    Astaxanthin purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2025 Dec 8:501:140750. [Abstract]

    Customer Validation
     Panels show typical images of hyperemia and Alcian blue–Alizarin red staining in the zebrafish anal fin, respectively. The zebrafish were exposed to 3 μM PFOS for two weeks. Astaxanthin or vitamin E was incorporated into the fodder during the second week of PFOS exposure. Black arrows indicate areas of hyperemia. The results showed that Astaxanthin (AX, 1% w/w in fodder; 0.1 mg/larva/day and 10 mg/adult/day for 4 weeks) significantly reversed the hyperemia around the anal fin joints and narrowed intraarticular space induced by PFOS.

  • 1/16

    Astaxanthin purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Mar 16:230:294-308. [Abstract]

    Customer Validation
     Representative images of mouse pancreatic tissues collected from the control, AP, and AP + Astaxanthin (ATX) groups (stained with H&E), and their pathology scores. H&E staining revealed that activation of Nrf2 by Astaxanthin (ATX, 40 mg/kg; single dose) significantly alleviated edema and inflammatory cell infiltration in mouse pancreatic tissue, and also markedly reduced the pathological scores of the pancreas.

  • 1/16

    Astaxanthin purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Mar 16:230:294-308. [Abstract]

    Customer Validation
     Fluorescent expression of Nrf2 in pancreatic tissues of the control, AP, AP + ML385, and AP + Astaxanthin (ATX; 10 μM; 1 h) groups. The results showed that Nrf2 expression decreased in the AP + ML385 group and increased in the AP + Astaxanthin group, in which nucleation was also favored.

  • 1/16

    Astaxanthin purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Mar 16:230:294-308. [Abstract]

    Customer Validation
     Astaxanthin (ATX, 40 mg/kg; single dose) activated Nrf2 expression in mouse pancreatic tissue via the Keap1/Nrf2 axis.

  • 1/16

    Astaxanthin purchased from MedChemExpress. Usage Cited in: Exp Biol Med. 2023 Feb;248(4):293-301. [Abstract]

    Customer Validation
     Astaxanthin (ASTA) decreases levels of caspase 3 and caspase 9 in MLE-12 cells, which reveals that ASTA prevents apoptosis stimulated by LPS in MLE-12 cells.

  • 1/16

    Astaxanthin purchased from MedChemExpress. Usage Cited in: Exp Biol Med. 2023 Feb;248(4):293-301. [Abstract]

    Customer Validation
     Astaxanthin (ASTA) inhibits apoptosis by targeting NF-κB signal pathway in MLE-12 cells.

  • Astaxanthin