1. Signaling Pathways
  2. Apoptosis
  3. Caspase
  4. Caspase 3 Isoform

Caspase 3

 

Caspase 3 Related Products (47):

Cat. No. Product Name Effect Purity
  • HY-12305
    Q-VD-OPh
    Inhibitor 99.78%
    Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12.
  • HY-12466
    Z-DEVD-FMK
    Inhibitor ≥98.0%
    Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 μM.
  • HY-19696
    Tauroursodeoxycholate
    Inhibitor ≥98.0%
    Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor.
  • HY-B1081A
    Oxidopamine hydrobromide
    Activator 99.95%
    Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine.
  • HY-P1001
    Ac-DEVD-CHO
    Inhibitor
    Ac-DEVD-CHO is a specific Caspase-3 inhibitor with a Ki value of 230 pM.
  • HY-108312A
    AC-VEID-CHO TFA
    Inhibitor ≥98.0%
    AC-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC50 values of 16.2 nM, 13.6 nM and 162.1 nM, respectively.
  • HY-W082785A
    L6H21
    Inhibitor
    L6H21, a Chalcone (HY-121054) derivative, is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor.
  • HY-P2614
    Mca-DEVDAP-K(Dnp)-OH
    Chemical
    Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3.
  • HY-19696A
    Tauroursodeoxycholate sodium
    Inhibitor 98.63%
    Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor.
  • HY-B1081
    Oxidopamine hydrochloride
    Activator 99.91%
    Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine.
  • HY-10805
    Almorexant
    Activator 99.01%
    Almorexant (ACT 078573) is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively.
  • HY-N0265
    Asperosaponin VI
    Inhibitor 98.73%
    Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway.
  • HY-121320
    Raptinal
    Inhibitor ≥98.0%
    Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis.
  • HY-13523
    PAC-1
    Activator 99.93%
    PAC-1 is a procaspase-3 activator that induces apoptosis in cancer cells with an EC50 of 2.08 μM.
  • HY-P1333
    Dynorphin A
    Activator 98.59%
    Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS).
  • HY-N0361
    Dihydrocapsaicin
    Inhibitor 98.82%
    Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist.
  • HY-10805A
    Almorexant hydrochloride
    Activator 99.94%
    Almorexant (ACT 078573) hydrochloride is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively.
  • HY-B1138
    Fenbufen
    Inhibitor 98.99%
    Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with analgetic and antipyretic effects.
  • HY-N3584
    Paris saponin VII
    Inhibitor 99.13%
    Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii Maxim.
  • HY-103667
    2-HBA
    Activator 98.42%
    2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.