1135695-98-5
Chemical Structure
Q-VD-OPh
Synonym(s): QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone
- CAS No.: 1135695-98-5
- Formula:C26H25F2N3O6
- Molecular Weight:513.49
IUPAC Name: (S)-5-(2,6-difluorophenoxy)-3-((S)-3-methyl-2-(quinoline-2-carboxamido)butanamido)-4-oxopentanoic acid
InChIKey: OOBJCYKITXPCNS-REWPJTCUSA-N
SMILES: O=C(O)C[C@H](NC([C@@H](NC(C1=NC2=CC=CC=C2C=C1)=O)C(C)C)=O)C(COC3=C(F)C=CC=C3F)=O
Biological Activity: Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Q-VD-OPh | 99.90% | Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier. | ||||||||||||||||||||
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Q-VD-OPh (GMP) | Q-VD-OPh (GMP) is Q-VD-OPh (HY-12305) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier. | |||||||||||||||||||||
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Q-VD-OPh (Standard) | ≥98% | Q-VD-OPh (Standard) is the analytical standard of Q-VD-OPh (HY-12305). This product is intended for research and analytical applications. Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier. | ||||||||||||||||||||
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