1. Signaling Pathways
  2. Cytoskeleton
  3. Integrin
  4. α5β1 Inhibitors

α5β1 Inhibitors

αvβ1

αvβ3

αvβ5

αvβ6

αvβ8

α5β1

α1β1

α2β1

α4β1

α6β1

α9β1

αIIbβ3

α4β7

αLβ2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform α5β1 together.

Please try each isoform separately.

α5β1 Specific Inhibitors & Antagonists
Product Name α5β1 αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α1β1 α4β1 α6β1 αIIbβ3 α4β7 αLβ2 α5β1 Selectivity Purity
MK-0429
α5β1, IC50: 12.2 nM (inhibition of fibronectin-binding)
αvβ1, IC50: 1.6 nM (inhibition of fibronectin-binding )
αvβ3, IC50: 2.8 nM (inhibition of vitronectin-binding)
αvβ5, IC50: 0.1 nM (inhibition of vitronectin-binding)
αvβ6, IC50: 0.7 nM (inhibition of LAP-binding)
αvβ8, IC50: 0.5 nM (inhibition of LAP-binding)
            Pan Antagonist 99.73%
BIO-1211
α5β1, IC50: >100 μM
         
α1β1, IC50: >100 μM
α4β1, IC50: 4 nM
α6β1, IC50: >100 μM
αIIbβ3, IC50: >100 μM
α4β7, IC50: 2 μM
αLβ2, IC50: >100 μM
Pan Inhibitor
Echistatin
α5β1
 
αvβ3
           
αIIbβ3
    Pan Antagonist
Echistatin TFA
α5β1
 
αvβ3
           
αIIbβ3
    Pan Antagonist