1. Signaling Pathways
  2. Apoptosis
  3. Caspase
  4. Caspase 3 Isoform
  5. Caspase 3 Inhibitor

Caspase 3 Inhibitor

Caspase 3 Inhibitors (26):

Cat. No. Product Name Effect Purity
  • HY-12305
    Q-VD-OPh
    Inhibitor 99.78%
    Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12.
  • HY-12466
    Z-DEVD-FMK
    Inhibitor ≥98.0%
    Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 μM.
  • HY-19696
    Tauroursodeoxycholate
    Inhibitor ≥98.0%
    Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor.
  • HY-P1001
    Ac-DEVD-CHO
    Inhibitor 98.66%
    Ac-DEVD-CHO is a specific Caspase-3 inhibitor with a Ki value of 230 pM.
  • HY-124832
    δ-Secretase inhibitor 11
    Inhibitor 99.06%
    δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC50 of 0.7 μM.
  • HY-108312A
    AC-VEID-CHO TFA
    Inhibitor ≥98.0%
    AC-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC50 values of 16.2 nM, 13.6 nM and 162.1 nM, respectively.
  • HY-19696A
    Tauroursodeoxycholate sodium
    Inhibitor 98.63%
    Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor.
  • HY-N0361
    Dihydrocapsaicin
    Inhibitor 99.59%
    Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist.
  • HY-N0265
    Asperosaponin VI
    Inhibitor 98.91%
    Asperosaponin VI, A saponin component from Dipsacus asper, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway.
  • HY-P0109A
    Z-FA-FMK
    Inhibitor ≥98.0%
    Z-FA-FMK ((1S)-Z-FA-FMK) is a potent Cathepsin B and L inhibitor.
  • HY-124476
    Cystamine
    Inhibitor 99.79%
    Cystamine is the disulfide form of the free thiol, cysteamine.
  • HY-N3584
    Paris saponin VII
    Inhibitor 99.13%
    Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii.
  • HY-B1138
    Fenbufen
    Inhibitor 98.99%
    Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with analgetic and antipyretic effects.
  • HY-P1095
    Ivachtin
    Inhibitor ≥99.0%
    Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM.
  • HY-114982
    KEA1-97
    Inhibitor 99.66%
    KEA1-97 is a selective Thioredoxin-caspase 3 interaction disruptor (IC50=10 μM).
  • HY-120838
    Heptelidic acid
    Inhibitor
    Heptelidic acid (Koningic acid) is a sesquiterpene antibiotic.
  • HY-N1157
    Thevetiaflavone
    Inhibitor
    Thevetiaflavone could upregulate the expression of Bcl‑2 and downregulate that of Bax and caspase‑3.
  • HY-12455
    Duocarmycin A
    Inhibitor
    Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA.
  • HY-W082785A
    L6H21
    Inhibitor
    L6H21, a Chalcone (HY-121054) derivative, is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor.
  • HY-N10018
    Cimiside E
    Inhibitor
    Cimiside E (25-Anhydrocimigenol xyloside) is a triterpene xyloside, Cimiside E possesses apoptotic action on gastric cancer cells, with an IC50 value of 14.58 μM.