1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. TRP Channel
  3. Dihydrocapsaicin

Dihydrocapsaicin 

Cat. No.: HY-N0361 Purity: 98.82%
Handling Instructions

Dihydrocapsaicin is a natural capsaicin, acts as a selective TRPV1 agonist, and also increases p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection.

For research use only. We do not sell to patients.

Dihydrocapsaicin Chemical Structure

Dihydrocapsaicin Chemical Structure

CAS No. : 19408-84-5

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5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
20 mg USD 140 In-stock
Estimated Time of Arrival: December 31
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Description

Dihydrocapsaicin is a natural capsaicin, acts as a selective TRPV1 agonist, and also increases p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection[1][2].

Molecular Weight

307.43

Formula

C₁₈H₂₉NO₃

CAS No.

19408-84-5

SMILES

CC(C)CCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (813.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2528 mL 16.2639 mL 32.5277 mL
5 mM 0.6506 mL 3.2528 mL 6.5055 mL
10 mM 0.3253 mL 1.6264 mL 3.2528 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (20.33 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6.25 mg/mL (20.33 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (20.33 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

DihydrocapsaicinTRP ChannelTransient receptor potential channelsInhibitorinhibitorinhibit

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Product Name:
Dihydrocapsaicin
Cat. No.:
HY-N0361
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