1. Signaling Pathways
  2. Apoptosis
  3. Bcl-2 Family
  4. Bcl-W Inhibitors

Bcl-W Inhibitors

Bcl-2

Bcl-xL

Bcl-W

Mcl-1

Bfl-1

Bcl-B

Bax

Bak

Bim

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Bcl-W together.

Please try each isoform separately.

Bcl-W Specific Inhibitors
Product Name Bcl-W Bcl-2 Bcl-xL Mcl-1 Bfl-1 Bcl-B Bcl-W Selectivity Purity
Venetoclax
Bcl-W, Ki: 245 nM
Bcl-2, Ki: 0.01 nM
Bcl-xL, Ki: 48 nM
      Pan Inhibitor 99.96%
Navitoclax
Bcl-W, Ki: 1 nM
Bcl-2, Ki: 1 nM
Bcl-xL, Ki: 1 nM
      Pan Inhibitor 99.97%
ABT-737
Bcl-W, EC50: 197.8 nM
Bcl-2, EC50: 30.3 nM
Bcl-xL, EC50: 78.7 nM
   
Bcl-B, EC50: 1820 nM
Pan Inhibitor 99.59%
A-1331852
Bcl-W, Ki: 4 nM
Bcl-2, Ki: 6 nM
Bcl-xL, Ki: 0.01 nM
Mcl-1, Ki: 142 nM
    Pan Inhibitor 99.81%
Obatoclax Mesylate
Bcl-W, Ki: 1-7 μM
Bcl-2, Ki: 220 nM
Bcl-xL, Ki: 1-7 μM
Mcl-1, Ki: 1-7 μM
 
Bcl-B, Ki: 1-7 μM
Pan Inhibitor 99.74%
A-1210477
Bcl-W, Ki: 2280 nM
Bcl-2, Ki: 132 nM
 
Mcl-1, Ki: 0.45 nM
Bfl-1, Ki: 660 nM
  Pan Inhibitor 98.89%
Gambogic Acid
Bcl-W, IC50: 2.02 μM
Bcl-2, IC50: 1.21 μM
Bcl-xL, IC50: 1.47 μM
Mcl-1, IC50: 0.79 μM
Bfl-1, IC50: 1.06 μM
Bcl-B, IC50: 0.66 μM
Pan Inhibitor 95.06%
Obatoclax
Bcl-W, Ki: 1-7 μM
BCL2, Ki: 200 nM
Bcl-xL, Ki: 1-7 μM
Mcl-1, Ki: 1-7 μM
 
Bcl-B, Ki: 1-7 μM
Pan Inhibitor