370572-36-4

MLS-0053105 Chemical Structure
370572-36-4

Chemical Structure

MLS-0053105

  • CAS No.: 370572-36-4
  • Formula:C15H14Cl3N3O2
  • Molecular Weight:374.65

InChIKey: ZGZGUAKCJRZXRV-UHFFFAOYSA-N

SMILES: O=C1C(Cl)=C(N2CCN(CC2)C)C(N1C3=CC=C(C(Cl)=C3)Cl)=O

Biological Activity: MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W, Bcl-2, and Bcl-XL and no activity against Bcl-B and Mcl-1[1].

Cat. No. Product Name Purity Description Pricing
HY-167881 		MLS-0053105 98.89% MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W, Bcl-2, and Bcl-XL and no activity against Bcl-B and Mcl-1.
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