1. PI3K/Akt/mTOR
  2. PI3K
  3. PI3KC2β Inhibitors

PI3KC2β Inhibitors

PI3Kα

PI3Kβ

PI3Kγ

PI3Kδ

PI3KC2α

PI3KC2β

PI3KC2γ

Vps34

PI3K

PI3KC3

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Sorry. There is currently no product that acts on isoform PI3KC2β together.

Please try each isoform separately.

PI3KC2β Specific Inhibitors
Product Name PI3KC2β PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2γ Vps34 PI3KC3 PI3KC2β Selectivity Purity
PI-103
PI3KC2β, IC50: 26 nM
p110α, IC50: 8 nM
p110β, IC50: 88 nM
p110γ, IC50: 150 nM
p110δ, IC50: 48 nM
PI3KC2α, IC50: 1 μM
 
hsVPS34, IC50: 2.3 μM
  Pan Inhibitor 99.86%
PIK-93
PI3KC2β, IC50: 140 nM
p110α, IC50: 39 nM
p110β, IC50: 590 nM
p110γ, IC50: 16 nM
p110δ, IC50: 120 nM
PI3KC2α, IC50: 16 μM
 
hsVPS34, IC50: 320 nM
  Pan Inhibitor 99.13%
PIK-75
PI3KC2β, IC50: 1 μM
p110α, IC50: 5.8 nM
p110β, IC50: 1.3 μM
p110γ, IC50: 76 nM
p110δ, IC50: 510 nM
PI3KC2α, IC50: 10 μM
 
hsVPS34, IC50: 2.6 μM
  Pan Inhibitor 99.91%
CH5132799
PI3KC2β, IC50: 5.3 μM
PI3Kα, IC50: 14 nM
PI3Kα-H1047R, IC50: 5.6 nM
PI3Kα-E545K, IC50: 6.7 nM
PI3Kα-E542K, IC50: 6.7 nM
PI3Kβ, IC50: 120 nM
PI3Kγ, IC50: 36 nM
PI3Kδ, IC50: 500 nM
        Pan Inhibitor >98.0%
A66
PI3K-C2β, IC50: 462 nM
p110α, IC50: 32 nM
p110α E545K, IC50: 30 nM
p110α H1047R, IC50: 43 nM
 
p110γ, IC50: 3480 nM
          Pan Inhibitor 99.26%
PIK-90
PI3KC2β, IC50: 64 nM
p110α, IC50: 11 nM
p110β, IC50: 350 nM
p110γ, IC50: 18 nM
p110δ, IC50: 58 nM
PI3KC2α, IC50: 47 nM
 
hsVPS34, IC50: 830 nM
  Pan Inhibitor 99.06%
PI3Kγ inhibitor 3
PI3KC2β, pIC50: 7.5
PI3Kα, pIC50: 5.1
PI3Kβ, pIC50: 4.5
PI3Kγ, pIC50: 9.1
PI3Kδ, pIC50: 6.5
PI3KC2α, pIC50: 5
PI3KC2γ, pIC50: 5.5
 
PI3KC3, pIC50: 5.1
Pan Inhibitor
CHMFL-PI3KD-317
PIK3C2B, IC50: 882.3 nM
PI3Kα, IC50: 62.6 nM
PI3Kβ, IC50: 284 nM
PI3Kγ, IC50: 202.7 nM
PI3Kδ, IC50: 6 nM
   
Vps34, IC50: 1801.7 nM
  Pan Inhibitor