677338-12-4
677338-12-4
Chemical Structure
PIK-90
- CAS No.: 677338-12-4
- Formula:C18H17N5O3
- Molecular Weight:351.36
IUPAC Name: N-(7,8-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)nicotinamide
InChIKey: ZJAVHOMVDCMAMF-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=C(C3=NCCN13)C=CC(OC)=C2OC)C4=CC=CN=C4
Biological Activity: PIK-90 is a DNA-PK and PI3K inhibitor, which inhibits p110α, p110γ and DNA-PK with IC50s of 11, 18 and 13 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PIK-90 | 99.31% | PIK-90 is a DNA-PK and PI3K inhibitor, which inhibits p110α, p110γ and DNA-PK with IC50s of 11, 18 and 13 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-156371MIPS-21335 -
Similarity Score 0.66
HY-100886BAY1082439 -
Similarity Score 0.64
HY-182086Copanlisib-NH -
Similarity Score 0.64
HY-15346Copanlisib -
Similarity Score 0.63
HY-15346ACopanlisib dihydrochloride -
Similarity Score 0.62
HY-141690API3K-IN-19 hydrochloride -
Similarity Score 0.56
![7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine Chemical Structure](//file.medchemexpress.com/product_pic/hy-w366582.gif)
HY-W3665827-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine -
Similarity Score 0.47
HY-139577Ninerafaxstat -
Similarity Score 0.46
HY-N10261Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate -
Explore the MedChemAI to find more analogs
![7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w366582.gif)
