2132961-46-5
2132961-46-5
Chemical Structure
AZD3458
- CAS No.: 2132961-46-5
- Formula:C20H23N3O4S2
- Molecular Weight:433.54
IUPAC Name: (S)-N-(5-(2-(1-cyclopropylethyl)-7-(methylsulfonyl)-1-oxoisoindolin-5-yl)-4-methylthiazol-2-yl)acetamide
InChIKey: PAQUFWFUOVDUIO-NSHDSACASA-N
SMILES: O=C1N([C@@H](C)C2CC2)CC3=CC(C4=C(C)N=C(NC(C)=O)S4)=CC(S(=O)(C)=O)=C31
Biological Activity: AZD3458 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD3458 | 99.71% | AZD3458 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively. | ||||||||||||||||||||
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References
Keywords
