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  3. PI3Kγ inhibitor 3

PI3Kγ inhibitor 3 

Cat. No.: HY-112443
Handling Instructions

PI3Kγ inhibitor 3 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively.

For research use only. We do not sell to patients.

PI3Kγ inhibitor 3 Chemical Structure

PI3Kγ inhibitor 3 Chemical Structure

CAS No. : 2132961-46-5

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Description

PI3Kγ inhibitor 3 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively[1].

IC50 & Target[1]

PI3Kγ

9.1 (pIC50)

PI3Kα

5.1 (pIC50)

PI3Kβ

4.5 (pIC50)

PI3Kδ

6.5 (pIC50)

PI3KC2α

5 (pIC50)

PI3KC2β

7.5 (pIC50)

PI3KC2γ

5.5 (pIC50)

PI3KC3

5.1 (pIC50)

In Vitro

PI3Kγ inhibitor 3 (Compound 15) also inhibits PI3KC2α, PI3KC2β, PI3KC2γ, and PI3KC3 with pIC50s of <5, 7.5, 5.5, and 5.1, respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

433.54

Formula

C₂₀H₂₃N₃O₄S₂

CAS No.

2132961-46-5

SMILES

O=C1N([[email protected]@H](C)C2CC2)CC3=CC(C4=C(C)N=C(NC(C)=O)S4)=CC(S(=O)(C)=O)=C31

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
PI3Kγ inhibitor 3
Cat. No.:
HY-112443
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PI3Kγ inhibitor 3

Cat. No.: HY-112443