Caspase Inhibitors

Caspase 1

Caspase 2

Caspase 3

Caspase 4

Caspase 5

Caspase 6

Caspase 7

Caspase 8

Caspase 9

Caspase 10

Caspase 12

Caspase

Caspase 11

Caspase-13

Caspase Inducers, Inhibitors, Activators, Modulators & Chemicals

Product Name	Caspase 1	Caspase 2	Caspase 3	Caspase 4	Caspase 5	Caspase 6	Caspase 7	Caspase 8	Caspase 9	Caspase 10	Caspase 12	Caspase	Caspase 11	Caspase-13	Purity
Q-VD-OPh	Caspase-1, IC₅₀: 25-400 nM		Caspase-3, IC₅₀: 25-400 nM				Caspase-7, IC₅₀: 48 nM	Caspase-8, IC₅₀: 25-400 nM	Caspase-9, IC₅₀: 25-400 nM	Caspase-10, IC₅₀: 25-400 nM	Caspase-12, IC₅₀: 25-400 nM				99.78%
Z-VAD-FMK												Caspase			99.76%
Emricasan												Caspase			99.59%
Z-VAD(OMe)-FMK												Caspase			98.20%
Belnacasan	Caspase-1														99.99%
Ac-WEHD-AFC TFA	Caspase-1														98.02%
Caspase-9 Inhibitor III									Caspase-9						99.52%
Z-DEVD-FMK			Caspase-3, IC₅₀: 18 μM												≥98.0%
Z-IETD-FMK								Caspase-8							≥98.0%
VRT-043198	Caspase-1, Ki: 0.8 nM			Caspase-4, Ki: 0.6 nM											98.05%
Tauroursodeoxycholate			Caspase-3								Caspase-12				≥98.0%
Ac-FLTD-CMK	Caspase-1, IC₅₀: 46.7 nM			Caspase-4, IC₅₀: 1.49 μM	Caspase-5, IC₅₀: 329 nM										99.53%
Ac-DEVD-CHO	Caspase-1, Ki: 18 nM	Caspase-2, Ki: 1710 nM	Caspase 3, Ki: 0.23 nM	Caspase-4, Ki: 132 nM	Caspase-5, Ki: 205 nM	Caspase-6, Ki: 31 nM	Caspase-7, Ki: 1.6 nM	Caspase-8, Ki: 0.92 nM	Caspase-9, Ki: 60 nM	Caspase-10, Ki: 12 nM					98.66%
Oxidopamine hydrochloride			Caspase-3					Caspase-8	Caspase-9						99.91%
Tauroursodeoxycholate sodium			Caspase-3								Caspase-12				98.63%
Raptinal			Caspase 3												98.60%
Almorexant			Caspase-3												99.71%
Oxidopamine hydrobromide			Caspase-3					Caspase-8	Caspase-9						99.95%
Almorexant hydrochloride			Caspase-3												99.98%
Dynorphin A			Caspase 3												98.59%
BOC-D-FMK												Caspase
Terfenadine		Caspase-2		Caspase-4					Caspase-9						99.91%
Wedelolactone													Caspase-11		99.91%
Z-YVAD-FMK												Caspase			≥98.0%
Ac-YVAD-cmk	Caspase-1
Ginsenoside Rh2								Caspase-8	Caspase-9						98.11%
PAC-1			Procaspase-3, EC₅₀: 2.08 μM												99.93%
Guggulsterone												Caspase			99.83%
ML132	Caspase-1, IC₅₀: 34.9 nM			Caspase-4, IC₅₀: 1.27 μM	Caspase-5, IC₅₀: 0.85 μM			Caspase-8, IC₅₀: 4.18 μM	Caspase-9, IC₅₀: 2.85 μM						98.75%
Pralnacasan	Interleukin-1β converting enzyme, Ki: 1.4 nM														98.75%
5,7,4'-Trimethoxyflavone			Caspase-3												99.65%
TC11									Caspase-9						98.04%
Cystamine			Caspase 3, IC₅₀: 23.6 μM												99.79%
Asperosaponin VI			Caspase 3												98.91%
Dehydrocorydaline							Caspase-7	Caspase-8							99.01%
Fenbufen	Caspase-1, IC₅₀: 4.4 μM		Caspase-3, IC₅₀: 1.2 μM	Caspase-4, IC₅₀: 0.57 μM	Caspase-5, IC₅₀: 0.87 μM				Caspase-9, IC₅₀: 0.76 μM						98.99%
Z-WEHD-FMK	Caspase-1														≥98.0%
Z-FA-FMK		Caspase-2	Caspase-3			Caspase-6	Caspase-7								≥98.0%
Dihydrocapsaicin			Caspase 3												99.86%
PETCM			Caspase 3												99.36%
Paris saponin VII			Caspase-3						Caspase-9						99.13%
δ-Secretase inhibitor 11			Caspase-3, IC₅₀: 31.86 ± 1. μM					Caspase-8, IC₅₀: 86.71 ± 10 μM							99.06%
Z-LEHD-FMK									Caspase-9						≥98.0%
MPT0B392												Caspase			≥99.0%
Ivachtin			Caspase-3, IC₅₀: 23 nM												≥99.0%
KEA1-97			Caspase 3, IC₅₀: 10 μM												99.66%
Chelidonic acid	Caspase-1
Arnicolide D												Caspase			99.20%
Nivalenol												Caspase			≥99.0%
Heptelidic acid			Caspase-3
Ossirene	Caspase-1														≥98.0%
2-HBA			Caspase-3							Caspase-10					99.09%
Z-VDVAD-FMK		Caspase-2													≥98.0%
Dehydrotrametenolic acid			Caspase-3												99.95%
Destruxin B			Caspase-3												99.35%
Cystamine (dihydrochloride）			Caspase 3, IC₅₀: 23.6 μM												≥98.0%
AC-VEID-CHO TFA			Caspase 3, IC₅₀: 13.6 nM			Caspase-6, IC₅₀: 16.2 nM	Caspase-7, IC₅₀: 162.1 nM								≥98.0%
EP1013												Caspase
CZL55	Caspase-1, IC₅₀: 24 nM														98.70%
Biotin-VAD-FMK												Caspase			≥98.0%
MX1013												Caspase			≥99.0%
Thevetiaflavone			Caspase-3												≥98.0%
PARP-1-IN-2			Caspase-3						Caspase-9						98.80%
5,7-Dihydroxychromone			Caspase-3						Caspase-9						99.98%
Boc-Asp(OMe)-fluoromethyl ketone												Caspase			≥98.0%
cRIPGBM chloride	Caspase-1														99.73%
Duocarmycin A			Procaspase-3						Caspase-9
cRIPGBM	Caspase-1
L6H21			Caspase 3
Z-LEED-FMK	Caspase-1			Caspase-4										Caspase-13
15-Acetoxyscirpenol												Caspase			99.35%
Akt1/Akt2-IN-2			Caspase-3
Ganoderic acid T1			Caspase 3						Caspase-9
Mca-DEVDAP-K(Dnp)-OH			Caspase-3
Cimiside E			Caspase 3
Caspase-8-IN-1								Caspase-8
Ac-WEHD-AFC	Caspase-1
Caspase-3/7 activator 2			Caspase-3				Caspase-7
BRD4 Inhibitor-15			Caspase-3 Procaspase-3
Apoptotic agent-2			Caspase 3
N1,N11-Diethylnorspermine			Caspase 3
Caspase-3/7 activator 1			Caspase-3				Caspase-7
PROTAC BRD4 Degrader-6			Caspase 3
BBR-BODIPY									Caspase-9
KDM1/CDK1-IN-1			Caspase-3
MMPSI			human Caspase-3, IC₅₀: 1.7 μM
Z-LEHD-FMK TFA									Caspase-9
LSD1-IN-26			Caspase-3						Caspase-9
Ac-Tyr-Val-Lys-Asp-aldehyde	Caspase-1
Anticancer agent 64			Caspase 3				Caspase-7
Bcl-2-IN-6							Caspase-7
Dynorphin A TFA			Caspase-3
Aviculin							Caspase-7		Caspase-9
Aspidin BB			Caspase-3
Bcl-2-IN-7							Caspase-7
Astin B			Caspase-3						Caspase-9
CDK1/2/4-IN-1			Caspase 3
Z-LEVD-FMK				Caspase-4
Apoptotic agent-3			Caspase 3
Anticancer agent 43			Caspase 3
Lycopodine			Caspase-3
Mca-YVADAP-Lys(Dnp)-OH	Caspase-1
TD1092			Caspase 3				Caspase-7
28-Deoxonimbolide			Caspase-3					Caspase-8	Caspase-9
Caspase-3-IN-1	Caspase-1, IC₅₀: >10000 nM		Caspase-3, IC₅₀: 14.5 ± 1.6 nM			Caspase-6, IC₅₀: >5000 nM	Caspase-7, IC₅₀: 21.8 ± 3.5 nM	Caspase-8, IC₅₀: >50000 nM
Caspase-3/7 activator 3			Caspase-3				Caspase-7
Ac-YVAD-CHO acetate	Caspase-1
Ac-DEVD-CMK			Caspase-3
Anticancer agent 63			Caspase-3
Sanggenon G			Caspase-3					Caspase-8	Caspase-9
Ac-Trp-Glu-His-Asp-Aldehyde	Caspase-1, Ki: 56 pM
Ganoderic acid Mk			Caspase-3						Caspase-9
p-nitro-Pifithrin-α			Caspase-3
Ac-YVAD-CHO	Caspase-1

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