1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. TRP Channel
  4. TRPC6 Isoform

TRPC6

 

TRPC6 Related Products (4):

Cat. No. Product Name Effect Purity
  • HY-101795
    Larixyl acetate
    Inhibitor 99.44%
    Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.
  • HY-161766
    L687
    Activator 99.49%
    L687 is a potent activator of TRPC3/C6/C7 that can induce cellular uptake of oligonucleotides.
  • HY-179490
    AM-0883
    Agonist
    AM-0883 is a TRPC6 (Transient receptor potential canonical 6) agonist (hTRPC6 EC50 = 46 nM). AM-0083 can be used for the study of cardiac and renal diseases.
  • HY-162090
    TRPC antagonist 1
    Antagonist
    TRPC antagonist 1 (compound 15g) is a potent TRP channel (TRPC) antagonist with IC50s of 2.4 μM, 12.2 μM, 7.6 μM, 2.9 μM, and 3.4 μM for TRPC3, TRPC4, TRPC5, TPRC6, and TRPC7, respectively. TRPC antagonist 1 displays noteworthy anti-glioblastoma efficacy in vitro against U87 cell lines.