2. Signaling Pathways
  3. Apoptosis
  4. Caspase
  5. Caspase 2 Isoform

Caspase 2

 

Caspase 2 Related Products (8):

Cat. No. Product Name Effect Purity
  • HY-P1001
    Ac-DEVD-CHO
    		Inhibitor 99.76%
    Ac-DEVD-CHO is a specific Caspase-3 inhibitor with a Ki value of 230 pM.
  • HY-B1193
    Terfenadine
    		Activator 99.91%
    Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
  • HY-P1008
    Z-VDVAD-FMK
    		Inhibitor ≥98.0%
    Z-VDVAD-FMK is a special inhibitor of caspase-2. Z-VDVAD-FMK produces a reduction in Lovastatin-induced apoptosis.
  • HY-P0109A
    Z-FA-FMK
    		Inhibitor 99.14%
    Z-FA-FMK ((1S)-Z-FA-FMK) is a potent Cathepsin B and L inhibitor. Z-FA-FMK blocks the induction of DEVDase activity, DNA fragmentation, and externalization of phosphatidylserine by selective synthetic retinoid-related molecules (RRMs). Z-FA-FMK inhibits apoptosis. Z-FA-FMK inhibits caspase activity and selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Z-FA-FMK is a viral inhibitor. Z-FA-FMK inhibits reovirus replication in a susceptible host.
  • HY-134567A
    Ac-VDVAD-CHO TFA
    		Inhibitor 99.15%
    Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC50: 46 and 15 nM).
  • HY-P10147
    Ac-LDESD-AMC
    		Inhibitor
    Ac-LDESD-AMC is a caspase-2 inhibitor. Ac-LDESD-AMC has a peptide sequence of Leu-Asp-Glu-Ser-Asp.
  • HY-P2012
    TRP-601
    		Inhibitor
    TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia.
  • HY-134567
    Ac-VDVAD-CHO
    		Inhibitor
    Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM).
Cat. No. Product Name / Synonyms Application Reactivity