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Cat. No.: HY-134567

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Ac-VDVAD-CHO

Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM).

For research use only. We do not sell to patients.

CAS No.: 194022-51-0
Formula: C₂₃H₃₇N₅O₁₀
Molecular Weight:543.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ac-VDVAD-CHO Chemical Structure

CAS No.: 194022-51-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM)^[1].

IC₅₀ & Target^[1]

Caspase-2

46 nM (IC₅₀)

Caspase-3

15 nM (IC₅₀)

All Caspase Isoforms :

Chemical Information

CAS No. 194022-51-0
Molecular Weight 543.57
Formula C₂₃H₃₇N₅O₁₀
Sequence

Ac-Val-Asp-Val-Ala-Asp-CHO
Sequence Shortening

Ac-VDVAD-CHO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Ac-VDVAD-CHO

All Caspase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ac-VDVAD-CHO Related Classifications

HY-134567 Related Classifications