1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. HSP90 Inhibitors

HSP90 Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

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Sorry. There is currently no product that acts on isoform HSP90 together.

Please try each isoform separately.

HSP90 Specific Inhibitors
Product Name HSP90 HSP70 HSP90 Selectivity Purity
Luminespib
HSP90α, IC50: 7.8 nM
HSP90β, IC50: 21 nM
GRP94, IC50: 535 nM
TRAP-1, IC50: 85 nM
Selective Inhibitor 99.14%
KW-2478
HSP90α, IC50: 3.8 nM
  Selective Inhibitor >98.0%
Onalespib
HSP90, Kd: 0.71 nM
  Selective Inhibitor 99.64%
Alvespimycin hydrochloride
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
  Selective Inhibitor 99.32%
BIIB021
HSP90, Ki: 1.7 nM
  Selective Inhibitor 99.93%
Debio 0932
HSP90α, IC50: 100 nM
HSP90β, IC50: 103 nM
  Selective Inhibitor 99.44%
NVP-HSP990
HSP90α, IC50: 0.6 nM
HSP90β, IC50: 0.8 nM
GRP94, IC50: 8.5 nM
TRAP1 ATPase, IC50: 320 nM
Selective Inhibitor 98.98%
PU-WS13
GRP94, EC50: 0.22 μM
HSP90α, EC50: 27.3 μM
HSP90β, EC50: 41.8 μM
TRAP-1, EC50: 7.3 μM
Selective Inhibitor 95.69%
VER-82576
HSP90β, IC50: 58 nM
GRP94, IC50: 4.1 μM
TRAP-1, IC50: 5.5 μM
Selective Inhibitor 99.48%
XL888
HSP90, IC50: 24 nM
  Selective Inhibitor 99.24%
Tanespimycin Hydrochloride
HSP90, IC50: 5 nM
  Selective Inhibitor 98.23%
Ethoxyquin
HSP90
  Selective Inhibitor 98.05%
VER-50589
HSP90, IC50: 21 nM
  Selective Inhibitor >98.0%
SNX-5422 Mesylate
HSP90, Kd: 41 nM
  Selective Inhibitor
Alvespimycin
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
  Selective Inhibitor
VER-49009
HSP90, IC50: 25 nM
  Selective Inhibitor 99.26%
Retaspimycin
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM
  Selective Inhibitor
TAS-116
HSP90α, Ki: 34.7 nM
HSP90β, Ki: 21.3 nM
  Selective Inhibitor