1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  3. HSP
  4. HSP90 Inhibitors

HSP90 Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

HSPA5

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Sorry. There is currently no product that acts on isoform HSP90 together.

Please try each isoform separately.

HSP90 Specific Inhibitors & Activators
Product Name HSP90 HSP90 Selectivity Purity
Tanespimycin
HSP90, IC50: 5 nM
Selective Inhibitor 99.03%
Geldanamycin
HSP90, Kd: 1.2 μM
Selective Inhibitor 99.78%
Luminespib
HSP90α, IC50: 7.8 nM
HSP90β, IC50: 21 nM
GRP94, IC50: 535 nM
Selective Inhibitor 99.81%
AMP-PCP disodium
HSP90, Kd: 3.8 μM
Selective Activator >99.0%
Alvespimycin
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
Selective Inhibitor
Ganetespib
HSP90
Selective Inhibitor 99.94%
Gamitrinib TPP hexafluorophosphate
HSP90
Selective Inhibitor 99.26%
Alvespimycin hydrochloride
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
Selective Inhibitor 98.72%
Onalespib
HSP90, Kd: 0.71 nM
Selective Inhibitor 99.96%
BIIB021
HSP90, Ki: 1.7 nM
HSP90, EC50: 38 nM
Selective Inhibitor 99.93%
PU-WS13
GRP94, EC50: 0.22 μM
HSP90α, EC50: 27.3 μM
HSP90β, EC50: 41.8 μM
Selective Inhibitor 99.34%
NVP-HSP990
HSP90α, IC50: 0.6 nM
HSP90β, IC50: 0.8 nM
GRP94, IC50: 8.5 nM
Selective Inhibitor 98.98%
Debio 0932
HSP90α, IC50: 100 nM
HSP90β, IC50: 103 nM
Selective Inhibitor 99.97%
XL888
HSP90, IC50: 24 nM
Selective Inhibitor 99.24%
TAS-116
HSP90α, Ki: 34.7 nM
HSP90β, Ki: 21.3 nM
Selective Inhibitor 98.96%
Grp94 Inhibitor-1
GRP94, IC50: 2 nM
Selective Inhibitor 99.18%
KW-2478
HSP90α, IC50: 3.8 nM
Selective Inhibitor >98.0%
Radicicol
HSP90, IC50: 1 μM
Selective Inhibitor >99.0%
VER-82576
HSP90β, IC50: 58 nM
GRP94, IC50: 4.1 μM
Selective Inhibitor 99.56%
VER-49009
HSP90, IC50: 25 nM
Selective Inhibitor 99.26%
Ethoxyquin
HSP90
Selective Inhibitor 98.29%
VER-50589
HSP90, IC50: 21 nM
Selective Inhibitor 99.85%
Cucurbitacin D
HSP90
Selective Inhibitor >98.0%
YZ129
HSP90
Selective Inhibitor
NMS-E973
HSP90α, DC50: 10 nM
Selective Inhibitor
Geldanamycin-FITC
HSP90
Selective Inhibitor
17-AEP-GA
HSP90
Selective Inhibitor
HS-27
HSP90
Selective Inhibitor
AMP-PCP
HSP90, Kd: 3.8 μM
Selective Activator
Tamoxifen
HSP90
Pan Activator 99.95%
Tamoxifen Citrate
HSP90
Pan Activator 99.55%
17-GMB-APA-GA
HSP90
Pan Inhibitor
Tamoxifen-​d5
HSP90
Pan Activator
Dihydroberberine
HSP90
Pan Inhibitor
Aminohexylgeldanamycin
HSP90
default Inhibitor