Hsp90: a specialized but essential protein-folding tool

  • J Cell Biol. 2001 Jul 23;154(2):267-73. doi: 10.1083/jcb.200104079.
J C Young  1 I Moarefi F U Hartl
Affiliations
  • 1. Cellular Biochemistry, Max Planck Institute for Biochemistry, Martinsried D-82152, Germany.
Abstract

HSP90 is unique among molecular chaperones. The majority of its known substrates are signal transduction proteins, and recent work indicates that it uses a novel protein-folding strategy.