467214-20-6
467214-20-6
Chemical Structure
Alvespimycin
Synonym(s): 17-DMAG; KOS-1022; NSC 707545
- CAS No.: 467214-20-6
- Formula:C32H48N4O8
- Molecular Weight:616.75
IUPAC Name: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-((2-(dimethylamino)ethyl)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
InChIKey: KUFRQPKVAWMTJO-LMZWQJSESA-N
SMILES: C/C1=C\C=C/[C@@H]([C@H](/C(C)=C/[C@@H]([C@H]([C@H](C[C@@H](CC(C(C(NC1=O)=CC2=O)=O)=C2NCCN(C)C)C)OC)O[H])C)OC(N)=O)OC
Biological Activity: Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Alvespimycin | 99.52% | Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 nM. | ||||||||||||||||||||
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Alvespimycin (Standard) | ≥98% | Alvespimycin (Standard) is the analytical standard of Alvespimycin (HY-10389). This product is intended for research and analytical applications. Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 nM. | ||||||||||||||||||||
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