Alvespimycin (Standard)
Alvespimycin (Standard) is the analytical standard of Alvespimycin (HY-10389). This product is intended for research and analytical applications. Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 nM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98%
- CAS. Nr.: 467214-20-6
- Formel: C32H48N4O8
- Molecular Weight:616.75
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-10389
AlvespimycinHsp90 Inhibitor -
HY-15205
GanetespibHSP90 Inhibitor -
HY-10941
VER-155008Hsp70 Inhibitor -
HY-15230
GeldanamycinHsp90 Inhibitor -
HY-12024
Alvespimycin hydrochloride -
HY-14463
OnalespibHsp90 Inhibitor -
HY-10211
TanespimycinHSP90 Inhibitor -
HY-10215
LuminespibHSP90 Inhibitor -
HY-15984
VER-50589Apoptosis Inducer -
HY-100110
KNK437HSP Inhibitor -
HY-15096
MKT-077Hsp70 Inhibitor -
HY-101712
TRC051384HSP70 Inducer
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 467214-20-6
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Molecular Weight 616.75
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Formel C32H48N4O8
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SMILES
C/C1=C\C=C/[C@@H]([C@H](/C(C)=C/[C@@H]([C@H]([C@H](C[C@@H](CC(C(C(NC1=O)=CC2=O)=O)=C2NCCN(C)C)C)OC)O[H])C)OC(N)=O)OC
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Synonyms
17-DMAG (Standard); KOS-1022 (Standard); NSC 707545 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Ge J, et al. Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90. J Med Chem. 2006 Jul 27;49(15):4606-15. [Content Brief]
[2]. Hertlein E, et al. 17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition. Blood. 2010 Jul 8;116(1):45-53. [Content Brief]
[3]. Henke A, et al. Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90. Cancers (Basel). 2016 Aug 24;8(9). pii: E77. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Alvespimycin (Standard) Related Classifications
HY-10389R Related Classifications
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