747412-49-3
747412-49-3
Chemical Structure
Luminespib
Synonym(s): VER-52296; AUY922; NVP-AUY922
- CAS No.: 747412-49-3
- Formula:C26H31N3O5
- Molecular Weight:465.54
IUPAC Name: 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
InChIKey: NDAZATDQFDPQBD-UHFFFAOYSA-N
SMILES: O=C(C1=NOC(C2=CC(C(C)C)=C(O)C=C2O)=C1C3=CC=C(CN4CCOCC4)C=C3)NCC
Biological Activity: Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Luminespib | 99.40% | Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively. | ||||||||||||||||||||
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Luminespib (Standard) | ≥98% | Luminespib (Standard) is the analytical standard of Luminespib. This product is intended for research and analytical applications. Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-148963HSP90-IN-20 -
Similarity Score 0.89
HY-10976Luminespib analog -
Similarity Score 0.78
HY-145814HSP90-IN-9 -
Similarity Score 0.75
HY-149891HSP90-IN-23 -
Similarity Score 0.65
HY-15984VER-50589 -
Similarity Score 0.63
HY-164399ASST0116CL1 free base -
Similarity Score 0.63
HY-164399SST0116CL1 -
Similarity Score 0.56
HY-117051STA-2842 -
Similarity Score 0.53
HY-184245Hsp90-IN-48 -
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