STA-2842
STA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
For research use only. We do not sell to patients.
- CAS No.: 1046490-67-8
- Formula: C29H38N6O5
- Molecular Weight:550.65
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 1046490-67-8
-
Molecular Weight 550.65
-
Formula C29H38N6O5
-
SMILES
O=C(C1=NN=C(N1C2=CC=C(CN3CCOCC3)C=C2)C4=C(O)C=C(O)C(C(C)C)=C4)NCCN5CCOCC5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)