1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  3. HSP
  4. HSP70 Isoform

HSP70

 

HSP70 Related Products (14):

Cat. No. Product Name Effect Purity
  • HY-10941
    VER-155008
    Inhibitor 99.91%
    VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 μM, 2.6 μM, and 2.6 μM for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 μM for Hsp70.
  • HY-15098
    Apoptozole
    Inhibitor 99.81%
    Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 μM, respectively, and can induce apoptosis.
  • HY-15096
    MKT-077
    Inhibitor 98.05%
    MKT-077 is a rhodacyanine dye and also a heat shock protein 70 (Hsp70) inhibitor which exhibits significant antitumor activity.
  • HY-100110
    KNK437
    Inhibitor 98.03%
    KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.
  • HY-18669
    ML346
    Activator 98.71%
    ML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC50 of 4.6 μM for Hsp70.
  • HY-P3989
    Apratoxin A
    Inhibitor
    Apratoxin A, a cyanobacterial metabolite, mediates antiproliferative activity through the induction of G1 cell cycle arrest and an apoptotic cascade.
  • HY-10940
    Pifithrin-μ
    Inhibitor 99.53%
    Pifithrin-μ is an inhibitor of p53 and HSP70, with antitumor and neuroprotective activity.
  • HY-101712
    TRC051384
    Activator 98.01%
    TRC051384 is a heat shock protein 70 (HSP70) inducer.
  • HY-101026
    CCT251236
    ≥99.0%
    CCT251236 is an orally available pirin ligand from a heat shock transcription factor 1 (hsf1) phenotypic screen with an IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction.
  • HY-12622
    HSP70-IN-1
    Inhibitor 98.05%
    HSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM.
  • HY-124805
    MAL3-101
    Inhibitor 98.60%
    MAL3-101 is a potent HSP70 allosteric inhibitor.
  • HY-120909
    YK5
    Inhibitor
    YK5 is a potent and selective Hsp70 inhibitor.
  • HY-138820
    SW02
    Activator
    SW02 is a potent activator of ATPase activity of Hsp70, with an EC50 of 150 μM.
  • HY-145857
    GRP78-IN-1
    Inhibitor
    GRP78-IN-1 exhibits several interactions with GRP78 residues with binding energy of -8.07 kcal/mol.