1134156-31-2
1134156-31-2
Chemical Structure
VER-155008
- CAS No.: 1134156-31-2
- Formula:C25H23Cl2N7O4
- Molecular Weight:556.40
IUPAC Name: 4-((((2R,3S,4R,5R)-5-(6-amino-8-((3,4-dichlorobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile
InChIKey: ZXGGCBQORXDVTE-UMCMBGNQSA-N
SMILES: NC1=C2N=C(NCC3=CC=C(Cl)C(Cl)=C3)N([C@@H]([C@H](O)[C@@H]4O)O[C@@H]4COCC5=CC=C(C#N)C=C5)C2=NC=N1
Biological Activity: VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 μM, 2.6 μM, and 2.6 μM for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 μM for Hsp70.
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VER-155008 | 99.82% | VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 μM, 2.6 μM, and 2.6 μM for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 μM for Hsp70. | ||||||||||||||||||||
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Keywords
