Poly (I:C):Kanamycin (1:1)

Name: Poly (I:C):Kanamycin (1:1)
Brand: MedChemExpress
SKU: HY-107202A
Rating: 5.0 (13 reviews)

Cat. No.: HY-107202A Assay: 51.00%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Poly (I:C):Kanamycin (1:1) is a mixture of poly (I:C) and kanamycin. Poly(I:C) is a synthetic double-stranded RNA (dsRNA), which is a Toll-like receptor 3 (TLR3) agonist. Kanamycin is positively charged (poly-NH3) and can thus neutralize the negative charge of Poly I:C and thereby stabilized the molecule.

For research use only. We do not sell to patients.

Poly (I:C):Kanamycin (1:1) Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 58	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 570	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 13 publication(s) in Google Scholar

Other Forms of Poly (I:C):Kanamycin (1:1):

Polyinosinic-polycytidylic acid In-stock
Polyinosinic-polycytidylic acid sodium In-stock
Poly (I:C):Kanamycin (1:1) (sodium) In-stock

13 Publications Citing Use of MCE Poly (I:C):Kanamycin (1:1)

•SSRN. 2021 Apr 26.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Appearance

Solid

Color

White to off-white

SMILES

[Poly(I:C):Kanamycin(1:1)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic)

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 20 mg/mL (Infinity mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 51.00%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (241 KB)

Handling Instructions (2659 KB)

References

[1]. Matsumoto M, et al. TLR3: interferon induction by double-stranded RNA including poly(I:C). Adv Drug Deliv Rev. 2008 Apr 29;60(7):805-12. [Content Brief]