1. Signaling Pathways
  2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. TLR7 Inhibitors

TLR7 Inhibitors

TLR3

TLR8

TLR9

TLR2

TLR4

TLR7

TLR1

TLR6

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform TLR7 together.

Please try each isoform separately.

TLR7 Specific Inhibitors, Agonists & Antagonists
Product Name TLR7 TLR8 TLR7 Selectivity Purity
Imiquimod
TLR7
  Selective Agonist 99.96%
Imiquimod hydrochloride
TLR7
  Selective Agonist 99.80%
DSR-6434
TLR7, EC50: 7.2 nM (Human)
TLR7, EC50: 4.6 nM (Mice)
  Selective Agonist 99.49%
1V209
TLR7
  Selective Agonist 99.52%
LHC-165
TLR7
  Selective Agonist 98.17%
GSK2245035
TLR7
  Selective Agonist 99.79%
Imiquimod maleate
TLR7
  Selective Agonist
Enpatoran
TLR7, IC50: 11.1 nM (in HEK293 cells)
TLR7, IC50: 68.3 nM (in peripheral blood mononuclear cells (PBMCs))
TLR7, IC50: 2.2 nM ( in whole blood (WB) cells)
TLR8, IC50: 24.1 nM (in HEK293 cells)
TLR8, IC50: 620 nM (in peripheral blood mononuclear cells (PBMCs))
TLR8, IC50: 120 nM ( in whole blood (WB) cells)
Pan Inhibitor
CU-115
TLR7, IC50: 50 μM
TLR8, IC50: 1.04 μM
Pan Antagonist
Gardiquimod diTFA
TLR7
TLR8
Agonist 99.77%