1. Signaling Pathways
  2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. TLR7 Inhibitors

TLR7 Inhibitors

TLR3

TLR8

TLR9

TLR2

TLR4

TLR7

TLR1

TLR6

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform TLR7 together.

Please try each isoform separately.

TLR7 Specific Inhibitors, Agonists & Antagonists
Product Name TLR7 TLR8 TLR9 TLR7 Selectivity Purity
Enpatoran hydrochloride
TLR7, IC50: 11.1 nM
TLR8, IC50: 24.1 nM
  Selective Inhibitor 98.82%
CL264
TLR7
    Selective Inhibitor 98.63%
TLR7 agonist 3
TLR7
    Selective Agonist 98.35%
Imiquimod
TLR7
    Selective Agonist 99.96%
Imiquimod hydrochloride
TLR7
    Selective Agonist 99.80%
DSR-6434
TLR7, EC50: 7.2 nM (Human)
TLR7, EC50: 4.6 nM (Mice)
    Selective Agonist 99.49%
1V209
TLR7
    Selective Agonist 99.52%
GSK2245035
TLR7
    Selective Agonist 99.79%
LHC-165
TLR7
    Selective Agonist 98.17%
Imiquimod maleate
TLR7
    Selective Agonist
TLR7 agonist 1
TLR7, IC50: 90 nM
    Selective Agonist
BBIQ
TLR7, EC50: 59.1 nM (Human TLR7)
    Selective Agonist
TLR7/8 agonist 3
TLR7
TLR8
  Selective Agonist 99.02%
Enpatoran
TLR7, IC50: 11.1 nM (in HEK293 cells)
TLR7, IC50: 68.3 nM (in peripheral blood mononuclear cells (PBMCs))
TLR7, IC50: 2.2 nM ( in whole blood (WB) cells)
TLR8, IC50: 24.1 nM (in HEK293 cells)
TLR8, IC50: 620 nM (in peripheral blood mononuclear cells (PBMCs))
TLR8, IC50: 120 nM ( in whole blood (WB) cells)
  Pan Inhibitor
AT791
TLR7, IC50: 3.33 μM
 
TLR9, IC50: 0.04 μM
Pan Inhibitor 98.77%
TLR8 agonist 2 hydrochloride
TLR7, EC50: 33.33 μM
TLR8, EC50: 3 nM
  Pan Agonist
TLR8 agonist 2
TLR7, EC50: 33.33 μM
TLR8, EC50: 3 nM
  Pan Agonist
TLR7/8 agonist 4
TLR7
TLR8
  Pan Agonist
AXC-715 hydrochloride
TLR7
TLR8
  Pan Agonist
CU-115
TLR7, IC50: 50 μM
TLR8, IC50: 1.04 μM
  Pan Antagonist
3M-011
TLR7
TLR8
  Pan Agonist
Gardiquimod diTFA
TLR7
TLR8
  Agonist ≥99.0%
Gardiquimod
TLR7
TLR8
  Agonist
TLR7/8-IN-1
TLR7
TLR8
  Inhibitor