1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)

Telratolimod (Synonyms: MEDI 9197; 3M 052)

Cat. No.: HY-109104
Handling Instructions

Telratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.

For research use only. We do not sell to patients.

Telratolimod Chemical Structure

Telratolimod Chemical Structure

CAS No. : 1359993-59-1

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Telratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.

IC50 & Target

TLR7/8[1]

In Vitro

Telratolimod (3M-052) is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].

In Vivo

Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6838 mL 8.4191 mL 16.8381 mL
5 mM 0.3368 mL 1.6838 mL 3.3676 mL
10 mM 0.1684 mL 0.8419 mL 1.6838 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

593.89

Formula

C₃₆H₅₉N₅O₂

CAS No.

1359993-59-1

SMILES

NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3OCCCCNC(CCCCCCCCCCCCCCCCC)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Telratolimod
Cat. No.:
HY-109104
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Telratolimod

Cat. No.: HY-109104