1. Signaling Pathways
  2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. TLR8 Inhibitors

TLR8 Inhibitors

TLR3

TLR8

TLR9

TLR2

TLR4

TLR7

TLR1

TLR6

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform TLR8 together.

Please try each isoform separately.

TLR8 Specific Inhibitors, Agonists & Antagonists
Product Name TLR8 TLR3 TLR9 TLR7 TLR8 Selectivity Purity
Selgantolimod
TLR8
      Selective Agonist 99.17%
CU-115
TLR8, IC50: 1.04 μM
   
TLR7, IC50: 50 μM
Selective Antagonist
CU-CPT-8m
TLR8, IC50: 67 nM
      Pan Antagonist 99.98%
CU-CPT-9a
TLR8, IC50: 0.5 nM
      Pan Antagonist 99.66%
CU-CPT9b
TLR8, IC50: 0.7 nM
TLR8, Kd: 21 nM
      Pan Antagonist 99.05%
CU-CPT17e
TLR8
TLR3
TLR9
  Pan Agonist 98.02%
Enpatoran
TLR8, IC50: 24.1 nM (in HEK293 cells)
TLR8, IC50: 620 nM (in peripheral blood mononuclear cells (PBMCs))
TLR8, IC50: 120 nM ( in whole blood (WB) cells)
   
TLR7, IC50: 11.1 nM (in HEK293 cells)
TLR7, IC50: 68.3 nM (in peripheral blood mononuclear cells (PBMCs))
TLR7, IC50: 2.2 nM ( in whole blood (WB) cells)
Pan Inhibitor
Gardiquimod diTFA
TLR8
   
TLR7
Agonist 99.77%