1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. CL264

CL264 

Cat. No.: HY-135905
Handling Instructions

CL264 is a TLR7-specific agonist for innate immune signals research.

For research use only. We do not sell to patients.

CL264 Chemical Structure

CL264 Chemical Structure

CAS No. : 1510712-69-2

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Description

CL264 is a TLR7-specific agonist for innate immune signals research[1].

IC50 & Target[1]

TLR7

 

In Vitro

Toll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7 is expressed predominantly in plasmacytoid dendritic cells (pDCs), macrophages and B cells. Many TLR7 modulators are interferon inducers, anti-cancer agents, anti-infectious agents, therapeutic agents for immunological diseases and vaccine adjuvants[1].

Molecular Weight

413.43

Formula

C₁₉H₂₃N₇O₄

CAS No.

1510712-69-2

SMILES

O=C(O)CNC(C1=CC=C(CN2C(NC3=C(N)N=C(NCCCC)N=C23)=O)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

CL264CL 264CL-264Toll-like Receptor (TLR)Inhibitorinhibitorinhibit

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