2. Disease Areas
  3. Inflammation or Immune System Disease
  4. Skin Inflammation
  5. Lupus Erythematosus

Lupus Erythematosus

Lupus erythematosus is a chronic autoimmune disease characterized by the immune system attacking the body's own tissues, leading to inflammation and damage across multiple organ systems. Systemic lupus erythematosus (SLE) is the most prevalent form, affecting approximately 70% of individuals with lupus, and can involve the skin, joints, kidneys, and other organs. Symptoms vary widely among patients and commonly include arthritis, fatigue, fever, and skin rashes, while more severe manifestations may involve neurological issues or organ damage. The disease has a variable clinical course and is associated with autoantibodies against DNA and RNA. Although the exact cause remains unknown, genetic, hormonal, and environmental factors are believed to contribute to its development, with family history slightly increasing risk. Early diagnosis and ongoing management are essential due to the absence of a cure, highlighting the importance of tailored treatment strategies to control symptoms and prevent complications.

Lupus Erythematosus (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-177933
    mNOX-E36
    mNOX-E36 is a murine-specific analogue of NOX-E36 (HY-148100), an anti-CCL-2 L-RNA aptamer that binds and neutralises the mouse chemokine CCL-2. mNOX-E36 reduces scarring in an experimental murine model of glaucoma filtration surgery (GFS). mNOX-E36 ameliorates lupus nephritis in mice. mNOX-E36 can be used for GFS and lupus nephritis research.
    mNOX-E36