1620278-72-9
1620278-72-9
Chemical Structure
TLR7/8 agonist 1 dihydrochloride
- CAS No.: 1620278-72-9
- Formula:C22H27Cl2N5
- Molecular Weight:432.39
IUPAC Name: 1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
InChIKey: YKZCFKIAMHQQAW-UHFFFAOYSA-N
SMILES: NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3CC4=CC=C(CN)C=C4.[H]Cl.[H]Cl
Biological Activity: TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline[1][2].
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TLR7/8 agonist 1 dihydrochloride | 99.70% | TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline. | ||||||||||||||||||||
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TLR7/8 agonist 1 dihydrochloride (Standard) | ≥98% | TLR7/8 agonist 1 dihydrochloride (Standard) is the analytical standard of TLR7/8 agonist 1 dihydrochloride (HY-103698A). This product is intended for research and analytical applications. TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline. | ||||||||||||||||||||
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References
- [1]. Shukla NM, et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6384-6. [Content Brief]
- [2]. Beesu M, et al. Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity. J Med Chem. 2015 Oct 8;58(19):7833-49. [Content Brief]
