2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Toll-like Receptor (TLR) ADC Cytotoxin
  4. E104

E104 (compound 1) is a potent and selective TLR7 agonist. E104 can be delivered by antibody-drug conjugate (ADC) technology to elicit potent anticancer activity. E104 induces the activation of mouse macrophages and hPBMCs.

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E104 Chemical Structure

E104 Chemical Structure

CAS No. : 1610431-21-4

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E104 Related Antibodies

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Description

E104 (compound 1) is a potent and selective TLR7 agonist. E104 can be delivered by antibody-drug conjugate (ADC) technology to elicit potent anticancer activity. E104 induces the activation of mouse macrophages and hPBMCs[1].

IC50 & Target[1]

TLR7

 

Molecular Weight

345.44

Formula

C21H23N5
CAS No.
SMILES

NC1=NC2=C(C=CC=C2)C3=C1N=C(CCCC)N3CC4=CC=C(C=C4)N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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E104 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E1041610431-21-4E 104E-104Toll-like Receptor (TLR)ADC CytotoxinADC PayloadanticancermacrophageshPBMCsInhibitorinhibitorinhibit

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