1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  3. HSP
  4. HSP Isoform

HSP

 

HSP Related Products (82):

Cat. No. Product Name Effect Purity
  • HY-100437
    HA15
    Inhibitor 99.62%
    HA15 is a potent and specific inhibitor of ER chaperone BiP/GRP78/HSPA5, inhibits the ATPase activity of BiP, with anti-cancerous activity.
  • HY-106443A
    Arimoclomol maleate
    Activator 99.96%
    Arimoclomol maleate (BRX-220) is a co-inducer of heat shock proteins (HSP).
  • HY-138280
    DTHIB
    Inhibitor 98.34%
    DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD).
  • HY-N0293
    Paeoniflorin
    Activator 98.04%
    Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity.
  • HY-124653
    HSP27 inhibitor J2
    Inhibitor 99.25%
    HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof.
  • HY-B0779
    Teprenone
    Activator 99.13%
    Teprenone is an anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).
  • HY-U00398
    Bimoclomol
    Activator 99.19%
    Bimoclomol is a heat shock protein (HSP) coinducer, used for treatment of cardiovascular diseases.
  • HY-117282
    JG-98
    Inhibitor 99.75%
    JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction.
  • HY-115467
    MitoBloCK-10
    98.80%
    MitoBloCK-10 (MB-10) is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity.
  • HY-138364
    YUM70
    Inhibitor ≥98.0%
    YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein.
  • HY-116683
    116-9e
    Inhibitor 98.55%
    116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor.
  • HY-139301
    DDO-5936
    Inhibitor
    DDO-5936 is a potent and specific Hsp90-Cdc37 PPI inhibitor.
  • HY-137441
    Icapamespib
    Inhibitor 99.52%
    Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5 nM.
  • HY-N6850
    Calenduloside E
    Inhibitor 98.47%
    Calenduloside E (CE) is a natural pentacyclic triterpenoid saponin extracted from Aralia elata.
  • HY-119046
    SNX-0723
    Inhibitor 99.15%
    SNX-0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.
  • HY-N1455
    Falcarinol
    Inhibitor ≥98.0%
    Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities.
  • HY-N3417
    Kongensin A
    Inhibitor ≥98.0%
    Kongensin A is a natural product isolated from Croton kongensis.
  • HY-120548
    KBU2046
    98.20%
    KBU2046 is an oral, highly selective inhibitor of cell motility and cell invasion in vitro.
  • HY-B0779A
    (5E,9E,13E)-Teprenone
    99.88%
    (5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity.
  • HY-P1896
    Hsp70-derived octapeptide
    98.01%
    Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs.