1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. HSP27 inhibitor J2

HSP27 inhibitor J2 (Synonyms: J2)

Cat. No.: HY-124653
Handling Instructions

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition.

For research use only. We do not sell to patients.

HSP27 inhibitor J2 Chemical Structure

HSP27 inhibitor J2 Chemical Structure

CAS No. : 2133499-85-9

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Description

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2].

IC50 & Target

HSP27[2]

Molecular Weight

264.30

Formula

C₁₃H₁₂O₄S

CAS No.

2133499-85-9

SMILES

O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2

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Please store the product under the recommended conditions in the Certificate of Analysis.

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HSP27 inhibitor J2
Cat. No.:
HY-124653
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