1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  3. HSP
  4. HSP Inhibitors

HSP Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

HSPA5

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

HSP Inhibitors, Antagonists & Activators
Product Name HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5 Purity
Tamoxifen    
HSP90
        99.92%
Tanespimycin    
HSP90, IC50: 5 nM
        99.07%
Geldanamycin    
HSP90, Kd: 1.2 μM
        99.78%
Ganetespib    
HSP90
        99.84%
MAL3-101  
HSP70
          98.60%
Novobiocin    
HSP90
       
Rocaglamide        
HSF1, IC50: 50 nM
    99.34%
VER-155008  
HSP70, IC50: 0.5 μM
HSC70, IC50: 2.6 μM
Grp78, IC50: 2.6 μM
          99.87%
Luminespib    
HSP90α, IC50: 7.8 nM
HSP90β, IC50: 21 nM
GRP94, IC50: 535 nM
        99.89%
Novobiocin sodium    
HSP90
        99.12%
Gamitrinib TPP hexafluorophosphate    
HSP90
        98.16%
Apoptozole  
HSP70, Kd: 0.14 μM
HSC70, Kd: 0.21 μM
          99.81%
Alvespimycin hydrochloride    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
        98.68%
Tamoxifen Citrate    
HSP90
        99.93%
Arimoclomol maleate          
HSP
  99.96%
Pimitespib    
HSP90α, Ki: 34.7 nM
HSP90β, Ki: 21.3 nM
        99.31%
Grp94 Inhibitor-1    
GRP94, IC50: 2 nM
        98.63%
MKT-077  
HSP70
          98.05%
KNK437
HSP40
HSP70
 
HSP105
      98.03%
KRIBB11        
HSF1, IC50: 1.2 μM
    99.12%
Onalespib    
HSP90, Kd: 0.71 nM
        99.62%
HSF1A        
HSF1
    99.43%
BIIB021    
HSP90, Ki: 1.7 nM
HSP90, EC50: 38 nM
        99.19%
ML346  
HSP70, EC50: 4.6 μM (HeLa cells)
          98.71%
Col003
HSP47, IC50: 1.8 μM
            99.30%
NVP-HSP990    
HSP90α, IC50: 0.6 nM
HSP90β, IC50: 0.8 nM
GRP94, IC50: 8.5 nM
        99.77%
TRC051384  
HSP70
          98.01%
Pifithrin-μ  
HSP70
          99.53%
Teprenone          
HSP
  99.13%
XL888    
HSP90, IC50: 24 nM
        99.62%
HM03            
HSPA5
98.06%
CCT251236  
HSP72, IC50: 19 nM (SK-OV-3 cells)
          ≥99.0%
Debio 0932    
HSP90α, IC50: 100 nM
HSP90β, IC50: 103 nM
        99.97%
Radicicol    
HSP90, IC50: 1 μM
        ≥99.0%
KW-2478    
HSP90α, IC50: 3.8 nM
        99.90%
VER-82576    
HSP90β, IC50: 58 nM
GRP94, IC50: 4.1 μM
        99.76%
HSP70-IN-1  
HSP70
          98.05%
Retaspimycin Hydrochloride    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM
        98.35%
NXP800        
HSF1
    99.79%
AMP-PCP disodium    
HSP90, Kd: 3.8 μM
        ≥99.0%
Chetomin    
HSP90
        ≥99.0%
Aminohexylgeldanamycin    
HSP90
        99.56%
Ethoxyquin    
HSP90
        98.29%
3-Phenyltoxoflavin    
HSP90, Kd: 585 nM
        99.86%
Geldanamycin-FITC    
HSP90
        98.02%
Cucurbitacin D    
HSP90
        99.91%
Dihydroberberine    
HSP90
        98.44%
VER-50589    
HSP90, IC50: 21 nM
        99.97%
VER-49009    
HSP90, IC50: 25 nM
        99.39%
Eupalinolide A        
HSF1
    99.92%
HS-27    
HSP90
        98.48%
NMS-E973    
HSP90α, DC50: 10 nM
        ≥98.0%
Gedunin    
HSP90
        ≥98.0%
NCT-58    
HSP90
        99.82%
PROTAC HSP90 degrader BP3    
HSP90
        98.56%
YZ129    
HSP90
        99.85%
Alvespimycin    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
       
Gamitrinib TPP    
HSP90
       
Tamoxifen-​d5    
HSP90
        99.77%
Bimoclomol          
HSP
  99.19%
Arimoclomol          
HSP
 
Arimoclomol citrate          
HSP
 
Cemdomespib    
HSP90
       
Shepherdin (79-87)    
HSP90
       
Macbecin    
HSP90, IC50: 2 μM
HSP90, Kd: 0.24 μM
       
YK5  
HSP70
HSP90
       
Colletofragarone A2    
HSP90
       
SW02  
TRAP1 ATPase, EC50: 150 ± 21 μM
         
Aminohexylgeldanamycin hydrochloride    
HSP90
       
Hsp90-IN-15    
HSP90
       
HSP90-IN-13    
HSP90, IC50: 25.07 nM
       
KU-177    
HSP90
       
HSP90-IN-9    
HSP90
       
HDAC/HSP90-IN-3    
HSP90, IC50: 0.83 μM (fungal Hsp90)
HSP90, IC50: 19.52 μM (human Hsp90)
       
17-AEP-GA    
HSP90
       
GRP78-IN-1  
Grp78
         
HDAC6/HSP90-IN-1    
HSP90, IC50: 46.8 nM
       
HSP90/mTOR-IN-1    
HSP90, IC50: 69 nM
       
CCT018159    
human Hsp90β, IC50: 3.2 μM
yeast Hsp90, IC50: 6.6 μM
       
17-GMB-APA-GA    
HSP90
       
HSP90-IN-14    
HSP90β, Kd: 0.26 ± 0.0 μM
       
AMP-PCP    
HSP90, Kd: 3.8 μM
       
MPC-0767    
HSP90
       
CH5138303    
HSP90α, Kd: 0.52 nM
       
Retaspimycin    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM