1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. Col003

Col003 

Cat. No.: HY-124817 Purity: >98.0%
Handling Instructions

Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix.

For research use only. We do not sell to patients.

Col003 Chemical Structure

Col003 Chemical Structure

CAS No. : 328565-16-8

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Description

Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].

IC50 & Target[1]

HSP47

1.8 μM (IC50)

Molecular Weight

257.24

Formula

C₁₄H₁₁NO₄

CAS No.

328565-16-8

SMILES

O=CC1=CC(CC2=CC=CC=C2)=CC([N+]([O-])=O)=C1O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References

Purity: >98.0%

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Col003
Cat. No.:
HY-124817
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