328565-16-8

Col003 Chemical Structure
328565-16-8

Chemical Structure

Col003

  • CAS No.: 328565-16-8
  • Formula:C14H11NO4
  • Molecular Weight:257.24

IUPAC Name: 5-benzyl-2-hydroxy-3-nitrobenzaldehyde

InChIKey: RKJXVCLOGNLZOI-UHFFFAOYSA-N

SMILES: O=CC1=CC(CC2=CC=CC=C2)=CC([N+]([O-])=O)=C1O

Biological Activity: Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis[1]

Cat. No. Product Name Purity Description Pricing
HY-124817
Col003 99.46% Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis
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