1. Metabolic Enzyme/Protease
    Neuronal Signaling
  2. COMT
  3. Nebicapone

Nebicapone (Synonyms: BIA 3-202)

Cat. No.: HY-106405
Handling Instructions

Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease..

For research use only. We do not sell to patients.

Nebicapone Chemical Structure

Nebicapone Chemical Structure

CAS No. : 274925-86-9

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Description

Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease.[1].

Molecular Weight

273.24

Formula

C₁₄H₁₁NO₅

CAS No.

274925-86-9

SMILES

O=C(C1=CC([N+]([O-])=O)=C(O)C(O)=C1)CC2=CC=CC=C2

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NebicaponeBIA 3-202COMTCatechol-O-methyltransferaseInhibitorinhibitorinhibit

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