1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. Paeoniflorin

Paeoniflorin (Synonyms: Peoniflorin)

Cat. No.: HY-N0293 Purity: 98.04%
Handling Instructions

Paeoniflorin (Peoniflorin), a heat shock protein-inducing compound and a pinane monoterpene glycoside with various bioactivities, such as anticancer effects, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, reducing blood viscosity and anti-inflammatory activity. paeoniflorin protects PC12 cells from MPP+ and acidic damage via autophagic pathway.

For research use only. We do not sell to patients.

Paeoniflorin Chemical Structure

Paeoniflorin Chemical Structure

CAS No. : 23180-57-6

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 185 In-stock
Estimated Time of Arrival: December 31
100 mg USD 168 In-stock
Estimated Time of Arrival: December 31
200 mg USD 300 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

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Customer Review

Based on 10 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Paeoniflorin purchased from MCE. Usage Cited in: J Food Nutr Res. 2018, 6(1), 26-31.

    LPS-induced RAW264.7 cells are pre-treated with the MCR extract (50 and 100 μg/mL), Paeoniflorin (10 and 30 μM), and Oxypaeoniflorin (10 and 30 μM) for 4 h and then co-treated with LPS (1 μg/ml) for 18 h. The expression of iNOS protein using western blot.

    Paeoniflorin purchased from MCE. Usage Cited in: Oral Dis. 2019 Nov;25(8):1945-1953.

    PF and BAI combination suppresses activation of the NF-κB signaling pathway in LPS-treated HOKs. Western blotting assay is performed to investigate expression of NF-κB inflammatory signaling proteins.

    Paeoniflorin purchased from MCE. Usage Cited in: Oral Dis. 2019 Nov;25(8):1945-1953.

    The nuclear translocation of NF-κB p65 was visualized using a laser confocal scanning microscope imaging system. Nuclei detected with DAPI (blue). Cells expressing NF-κB p65 in the cytoplasm (green). NF-κB p65 expresses mostly in the nucleus, and a small amount expressed in the cytoplasm (green). Localization of NF-κB p65 in the cytoplasm (green)

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    Description

    Paeoniflorin (Peoniflorin), a heat shock protein-inducing compound and a pinane monoterpene glycoside with various bioactivities, such as anticancer effects, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, reducing blood viscosity and anti-inflammatory activity. paeoniflorin protects PC12 cells from MPP+ and acidic damage via autophagic pathway[1][2][3].

    Clinical Trial
    Molecular Weight

    480.46

    Formula

    C₂₃H₂₈O₁₁

    CAS No.
    SMILES
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 100 mg/mL (208.13 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.0813 mL 10.4067 mL 20.8134 mL
    5 mM 0.4163 mL 2.0813 mL 4.1627 mL
    10 mM 0.2081 mL 1.0407 mL 2.0813 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2.5 mg/mL (5.20 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 2.5 mg/mL (5.20 mM); Clear solution

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.5 mg/mL (5.20 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References

    Purity: 98.04%

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    Keywords:

    PaeoniflorinPeoniflorinHSPHeat shock proteinsanticanceranti-oxidativestressantiplateletaggregationanti-inflammatoryPC12cellsautophagicpathwayInhibitorinhibitorinhibit

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    Product Name:
    Paeoniflorin
    Cat. No.:
    HY-N0293
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