1. Metabolic Enzyme/Protease
  2. HIF/HIF Prolyl-Hydroxylase

Paeoniflorin (Synonyms: Peoniflorin)

Cat. No.: HY-N0293 Purity: >98.0%
Data Sheet SDS Handling Instructions

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.

For research use only. We do not sell to patients.
Paeoniflorin Chemical Structure

Paeoniflorin Chemical Structure

CAS No. : 23180-57-6

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10 mM * 1 mL in DMSO $154 In-stock
100 mg $140 In-stock
200 mg $250 In-stock
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  • Biological Activity

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Description

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Target: Others Paeoniflorin (PF) is the principal bioactive component of Radix Paeo- niae alba, which is widely used in Traditional Chinese Medicine for the treatment of neurodegenerative disorders such as Parkinson's disease(PD) [1]. Paeoniflorin, a compound found in white peony that inhibited the production of testosterone and promoted the activity of aromatase, which converts testosterone into estrogen [2]. Treatment of cells with paeoniflorin but not glycyrrhizin resulted in enhanced phosphorylation and acquisition of the deoxyribonucleic acid-binding ability of heat shock transcription factor 1 (HSF1), as well as the formation of characteristic HSF1 granules in the nucleus, suggesting that the induction of HSPs by paeoniflorin is mediated by the activation of HSF1. Also, thermotolerance was induced by treatment with paeoniflorin but not glycyrrhizin. Paeoniflorin had no toxic effect at concentrations as high as 80 microg/ mL (166.4 microM). To our knowledge, this is the first report on the induction of HSPs by herbal medicines [3].

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References
Molecular Weight

480.46

Formula

C₂₃H₂₈O₁₁

CAS No.

23180-57-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 27 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: >98.0%

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Product Name:
Paeoniflorin
Cat. No.:
HY-N0293
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