1. Signaling Pathways
  2. Apoptosis
  3. Bcl-2 Family
  4. Bcl-B Inhibitors

Bcl-B Inhibitors

Bcl-2

Bcl-xL

Bcl-W

Mcl-1

Bfl-1

Bcl-B

Bax

Bak

Bim

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Bcl-B together.

Please try each isoform separately.

Bcl-B Specific Inhibitors
Product Name Bcl-B Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Selectivity Purity
ABT-737
Bcl-B, EC50: 1820 nM
Bcl-2, EC50: 30.3 nM
Bcl-xL, EC50: 78.7 nM
Bcl-W, EC50: 197.8 nM
    Pan Inhibitor 99.59%
Obatoclax Mesylate
Bcl-B, Ki: 1-7 μM
Bcl-2, Ki: 220 nM
Bcl-xL, Ki: 1-7 μM
Bcl-W, Ki: 1-7 μM
Mcl-1, Ki: 1-7 μM
  Pan Inhibitor 99.74%
Gambogic Acid
Bcl-B, IC50: 0.66 μM
Bcl-2, IC50: 1.21 μM
Bcl-xL, IC50: 1.47 μM
Bcl-W, IC50: 2.02 μM
Mcl-1, IC50: 0.79 μM
Bfl-1, IC50: 1.06 μM
Pan Inhibitor 95.06%
Obatoclax
Bcl-B, Ki: 1-7 μM
BCL2, Ki: 200 nM
Bcl-xL, Ki: 1-7 μM
Bcl-W, Ki: 1-7 μM
Mcl-1, Ki: 1-7 μM
  Pan Inhibitor