HSP90-IN-23
Based on 1 Customer Validation
HSP90-IN-23 (Comp 12-1) is an inhibitor of heat shock protein 90(HSP90) with an IC50 of 9 nM. HSP90-IN-23 induces apoptosis of tumor cells and arrests the tumor cell cycle in G0/G1 phase. HSP90-IN-23 can be used for cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.25%
- CAS. Nr.: 2944100-30-3
- Formel: C22H24N2O6S
- Molecular Weight:444.50
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
8.65 nM
Compound: 12-1
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Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
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[PMID: 37315698] |
| ES-2 | IC50 |
8.6 nM
Compound: 12-1
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Cytotoxicity against human ES2 cells by MTT assay
Cytotoxicity against human ES2 cells by MTT assay
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[PMID: 37315698] |
| HeLa | IC50 |
2 nM
Compound: 12-1
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Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
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[PMID: 37315698] |
| MCF7 | IC50 |
1.35 nM
Compound: 12-1
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Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
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[PMID: 37315698] |
| MDA-MB-231 | IC50 |
2.81 nM
Compound: 12-1
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Cytotoxicity against human MDA-MB-231 cells by MTT assay
Cytotoxicity against human MDA-MB-231 cells by MTT assay
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[PMID: 37315698] |
Chemical Information
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CAS. Nr. 2944100-30-3
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Appearance Solid
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Molecular Weight 444.50
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Formel C22H24N2O6S
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Color White to off-white
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SMILES
OC1=CC(O)=C(C=C1C(C)C)C2=C(C(C(NCC)=O)=NO2)C3=CC=C(C=C3)S(=O)(C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HSP90-IN-23 Related Classifications
HY-149891 Related Classifications
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