1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. Akt
  4. Akt Inhibitors

Akt Inhibitors

Akt

Akt1

Akt2

Akt3

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Akt Inhibitors, Agonists & Activators
Product Name Akt Akt1 Akt2 Akt3 Purity
MK-2206 dihydrochloride    
Akt2, IC50: 12 nM
Akt3, IC50: 65 nM
99.99%
Capivasertib    
Akt2, IC50: 7 nM
Akt3, IC50: 7 nM
99.95%
Ipatasertib    
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
99.88%
Oridonin    
Akt2, IC50: 8.9 μM
  99.89%
AKT inhibitor VIII    
Akt2, IC50: 210 nM
Akt3, IC50: 2119 nM
98.97%
GSK-690693    
Akt2, IC50: 13 nM
Akt3, IC50: 9 nM
98.46%
Miransertib    
Akt2, IC50: 14 nM
Akt3, IC50: 8.1 nM
99.32%
Afuresertib    
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
99.54%
Uprosertib    
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM
99.74%
Triciribine
Akt, IC50: 130 nM (cell assay)
      99.81%
A-443654    
Akt2, Ki: 160 pM
Akt3, Ki: 160 pM
98.50%
BAY1125976    
Akt2, IC50: 18 nM (at 10 μM ATP)
Akt3, IC50: 427 nM (at 10 μM ATP)
99.74%
Thymoquinone
Akt
      99.59%
Vevorisertib trihydrochloride    
Akt2, IC50: 0.81 nM
Akt3, IC50: 1.31 nM
99.13%
Ipatasertib dihydrochloride    
Akt2, IC50: 18 nM
Akt3, IC50: 8 nM
99.27%
AT13148    
Akt2, IC50: 402 nM
Akt3, IC50: 50 nM
99.21%
AT7867    
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
99.88%
Pifusertib hydrochloride    
Akt2, IC50: 1.6 nM
Akt3, IC50: 44 nM
98.96%
M2698      
Akt3, IC50: 1 nM
99.87%
INY-03-041    
Akt2, IC50: 6.8 nM
Akt3, IC50: 3.5 nM
98.64%
Afuresertib hydrochloride    
Akt2, Ki: 2 nM
Akt3, Ki: 2.6 nM
99.03%
CCT128930    
Akt2, IC50: 6 nM
  99.69%
ALM301    
Akt2, IC50: 0.09 μM
Akt3, IC50: 2.75 μM
99.33%
AT7867 dihydrochloride    
Akt2, IC50: 17 nM
Akt3, IC50: 47 nM
99.75%
4-Methylbenzylidene camphor
Akt
      99.87%
H-Ile-Lys-Val-Ala-Val-OH
Akt
      99.12%
MS170    
Akt2, Kd: 77 nM
Akt3, Kd: 6.5 nM
99.72%
3CAI    
Akt2
  99.97%
AKT-IN-6    
Akt2
Akt3
99.51%
Deltonin
Akt
      99.94%
Akt1/Akt2-IN-1    
Akt2, IC50: 42 nM
  99.59%
CCT128930 hydrochloride    
Akt2, IC50: 6 nM
  98.32%
Miransertib hydrochloride    
Akt2, IC50: 174 nM
Akt3, IC50: 8.1 nM
99.74%
AKT-IN-3    
Akt2, IC50: 1.2 nM
Akt3, IC50: 1.7 nM
99.29%
AT-533
Akt
      98.86%
MS15    
Akt2, IC50: 90 ± 2.8 nM
Akt3, IC50: 544 ± 2.9 nM
INY-03-041 trihydrochloride  
Akt1, IC50: 2.0 nM
Akt2, IC50: 6.8 nM
Akt3, IC50: 3.5 nM
99.27%
Pifusertib    
Akt2, IC50: 1.6 nM
Akt3, IC50: 44 nM
Akt1&PKA-IN-1
Akt, IC50: 0.11 μM
     
Akt1&PKA-IN-2  
Akt1, IC50: 0.007 μM
   
Isoprocurcumenol
Akt
     
MK-2206  
Akt1, IC50: 8 nM
Akt2, IC50: 12 nM
Akt3, IC50: 65 nM
Vevorisertib    
Akt2, IC50: 0.81 nM
Akt3, IC50: 1.31 nM
MS98    
Akt2, : 140 nM
Akt3, : 8.1 nM
Hu7691 free base    
Akt2, IC50: 97.5 nM
Akt3, IC50: 28 nM
Hu7691    
Akt2, IC50: 97.5 nM
Akt3, IC50: 28 nM
NTQ1062    
Akt2, IC50: 6.3 nM
Akt3, IC50: 0.1 nM
MK-2206 free base    
Akt2, IC50: 12 nM
Akt3, IC50: 65 nM
AKT-IN-5    
Akt2, IC50: 400 nM
 
Akt1/Akt2-IN-2  
Akt1, IC50: 138 nM
Akt2, IC50: 212 nM
Akt3, IC50: 7.2 mM
Coelonin
Akt
     
AKT-IN-8    
Akt2, IC50: 2.44 nM
Akt3, IC50: 9.47 nM
AKT-IN-13    
Akt2, IC50: 2.4 nM
Akt3, IC50: 0.3 nM
Eudebeiolide B
Akt
     
Tanshinol borneol ester
Akt
     
PTP1B-IN-24
Akt, IC50: 1.4 μM
     
Akt1-IN-4  
Akt1
   
AKT-IN-18
Akt, IC50: 69.45 μM
     
Uprosertib hydrochloride    
Akt2, IC50: 328 nM
Akt3, IC50: 38 nM
Akt1-IN-2  
Akt1, IC50: 4.6 μM
Akt2, IC50: >250 μM
Akt3, IC50: >250 μM