Akt Inhibitors

Akt

Akt1

Akt2

Akt3

Akt Inhibitors & Activators

Product Name	Akt	Akt1	Akt2	Akt3	Purity
MK-2206 dihydrochloride			Akt2, IC₅₀: 12 nM	Akt3, IC₅₀: 65 nM	99.92%
Akt1&PKA-IN-1	Akt, IC₅₀: 0.11 μM
Akt1&PKA-IN-2		Akt1, IC₅₀: 0.007 μM
Capivasertib			Akt2, IC₅₀: 7 nM	Akt3, IC₅₀: 7 nM	99.83%
Ipatasertib			Akt2, IC₅₀: 18 nM	Akt3, IC₅₀: 8 nM	99.88%
Oridonin			Akt2, IC₅₀: 8.9 μM		99.89%
GSK-690693			Akt2, IC₅₀: 13 nM	Akt3, IC₅₀: 9 nM	98.46%
AKT inhibitor VIII			Akt2, IC₅₀: 210 nM	Akt3, IC₅₀: 2119 nM	98.97%
Miransertib			Akt2, IC₅₀: 14 nM	Akt3, IC₅₀: 8.1 nM	99.33%
Afuresertib			Akt2, Ki: 2 nM	Akt3, Ki: 2.6 nM	99.54%
Triciribine	Akt, IC₅₀: 130 nM (cell assay)				99.81%
Uprosertib			Akt2, IC₅₀: 328 nM	Akt3, IC₅₀: 38 nM	99.74%
A-443654			Akt2, Ki: 160 pM	Akt3, Ki: 160 pM	98.50%
BAY1125976			Akt2, IC₅₀: 18 nM (at 10 μM ATP)	Akt3, IC₅₀: 427 nM (at 10 μM ATP)	99.74%
AT13148			Akt2, IC₅₀: 402 nM	Akt3, IC₅₀: 50 nM	99.42%
CCT128930			Akt2, IC₅₀: 6 nM		99.69%
Ipatasertib dihydrochloride			Akt2, IC₅₀: 18 nM	Akt3, IC₅₀: 8 nM	99.27%
Vevorisertib trihydrochloride			Akt2, IC₅₀: 0.81 nM	Akt3, IC₅₀: 1.31 nM	99.13%
Pifusertib hydrochloride			Akt2, IC₅₀: 1.6 nM	Akt3, IC₅₀: 44 nM	98.96%
AT7867			Akt2, IC₅₀: 17 nM	Akt3, IC₅₀: 47 nM	99.88%
M2698				Akt3, IC₅₀: 1 nM	99.81%
Afuresertib hydrochloride			Akt2, Ki: 2 nM	Akt3, Ki: 2.6 nM	99.03%
3CAI			Akt2		99.97%
AT7867 dihydrochloride			Akt2, IC₅₀: 17 nM	Akt3, IC₅₀: 47 nM	99.17%
INY-03-041			Akt2, IC₅₀: 6.8 nM	Akt3, IC₅₀: 3.5 nM	98.64%
Akt1/Akt2-IN-1			Akt2, IC₅₀: 42 nM		99.59%
AKT-IN-6			Akt2	Akt3	99.51%
CCT128930 hydrochloride			Akt2, IC₅₀: 6 nM		98.32%
Deltonin	Akt				99.93%
MS170			Akt2, Kd: 77 nM	Akt3, Kd: 6.5 nM
AKT-IN-3			Akt2, IC₅₀: 1.2 nM	Akt3, IC₅₀: 1.7 nM	99.29%
ALM301			Akt2, IC₅₀: 0.09 μM	Akt3, IC₅₀: 2.75 μM	99.33%
Pifusertib			Akt2, IC₅₀: 1.6 nM	Akt3, IC₅₀: 44 nM
MK-2206			Akt2, : 12 nM	Akt3, : 65 nM
Miransertib hydrochloride			Akt2, IC₅₀: 174 nM	Akt3, IC₅₀: 8.1 nM
MS15			Akt2, IC₅₀: 90 ± 2.8 nM	Akt3, IC₅₀: 544 ± 2.9 nM
Vevorisertib			Akt2, IC₅₀: 0.81 nM	Akt3, IC₅₀: 1.31 nM
Hu7691 free base			Akt2, IC₅₀: 97.5 nM	Akt3, IC₅₀: 28 nM
Hu7691			Akt2, IC₅₀: 97.5 nM	Akt3, IC₅₀: 28 nM
NTQ1062			Akt2, IC₅₀: 6.3 nM	Akt3, IC₅₀: 0.1 nM
INY-03-041 trihydrochloride		Akt1, IC₅₀: 2.0 nM	Akt2, IC₅₀: 6.8 nM	Akt3, IC₅₀: 3.5 nM	99.27%
MS98			Akt2, : 140 nM	Akt3, : 8.1 nM
AKT-IN-5			Akt2, IC₅₀: 400 nM
Akt1/Akt2-IN-2		Akt1, IC₅₀: 138 nM	Akt2, IC₅₀: 212 nM	Akt3, IC₅₀: 7.2 mM
Coelonin	Akt
AKT-IN-8			Akt2, IC₅₀: 2.44 nM	Akt3, IC₅₀: 9.47 nM
AKT-IN-13			Akt2, IC₅₀: 2.4 nM	Akt3, IC₅₀: 0.3 nM
Tanshinol borneol ester	Akt
AT-533	Akt				98.86%
H-Ile-Lys-Val-Ala-Val-OH	Akt
Isoprocurcumenol	Akt
Uprosertib hydrochloride			Akt2, IC₅₀: 328 nM	Akt3, IC₅₀: 38 nM

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