Zeaxanthin

Name: Zeaxanthin
Brand: MedChemExpress
SKU: HY-120318
Rating: 5.0 (2 reviews)

Cat. No.: HY-120318 Purity: 95.0%: Data Sheet
COA

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Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects.

For research use only. We do not sell to patients.

CAS No. : 144-68-3

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

2 Publications Citing Use of MCE Zeaxanthin

Cell Proliferation/Viability Assay

Cell Migration/Invasion Assay

Apoptosis Analysis

Histological Imaging/Staining

: Zeaxanthin purchased from MedChemExpress. Usage Cited in: Transl Oncol. 2026 Feb:64:102658. [Abstract]; Cell viability assessed by CCK-8 assay treated with Zeaxanthin (Zea) (98.17 μM).

: Zeaxanthin purchased from MedChemExpress. Usage Cited in: Transl Oncol. 2026 Feb:64:102658. [Abstract]; Cell migration detected by Transwell treated with Zeaxanthin (Zea) (98.17 μM).

: Zeaxanthin purchased from MedChemExpress. Usage Cited in: Transl Oncol. 2026 Feb:64:102658. [Abstract]; Cell apoptosis measured by flow cytometry treated with Zeaxanthin (Zea) (98.17 μM).

: Zeaxanthin purchased from MedChemExpress. Usage Cited in: Transl Oncol. 2026 Feb:64:102658. [Abstract]; WB analysis of MAPK/ERK pathway proteins. A549 cells: NC, Zeaxanthin (Zea) (98.17 μM).

: Zeaxanthin purchased from MedChemExpress. Usage Cited in: Transl Oncol. 2026 Feb:64:102658. [Abstract]; HE staining images of mouse tumor tissues treated with Zeaxanthin (Zea) (50 mg/kg, i.g.).

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Description

Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects^[1]^[2].

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

In Vitro

Much of the Lutein and Zeaxanthin in the leaves of plants is protein-bound.In fruits and flower petals, the xanthophylls are esterified and are concentrated into chromoplasts where they are found to be solubilized in the membranes. In humans and higher animals, Lutein and Zeaxanthin are accumulated in lipophilic tissues such as adipose tissue and are carried in the blood by the lipoproteins, probably in a nonspecific manner similar to cholesterol. Lutein and Zeaxanthin are distributed equally between LDL and HDL fractions in human blood, in contrast to the hydrocarbon carotenoids that are preferentially found in LDL fractions, up to 75%^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

568.87

Formula

C₄₀H₅₆O₂

CAS No.

144-68-3

Appearance

Solid

Color

Brown to reddish brown

SMILES

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](O)CC2(C)C)=C(C)C[C@@H](O)C1

Structure Classification

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility

In Vitro:

THF : ≥ 10 mg/mL (17.58 mM)

DMSO : 1 mg/mL (1.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7579 mL	8.7894 mL	17.5787 mL
5 mM	0.3516 mL	1.7579 mL	3.5157 mL
10 mM	0.1758 mL	0.8789 mL	1.7579 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (268 KB) SDS (393 KB)

COA (239 KB)

Handling Instructions (2659 KB)

References

[1]. Bone RA, et al. Distribution of lutein and zeaxanthin stereoisomers in the human retina. Exp Eye Res. 1997 Feb;64(2):211-8. [Content Brief]

[2]. Elbaz-Hayoun S, et al. Evaluation of antioxidant treatments for the modulation of macrophage function in the context of retinal degeneration. Mol Vis. 2019 Sep 5;25:479-488. [Content Brief]

[3]. Krinsky NI, et al. Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye.Annu Rev Nutr. 2003;23:171-201. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / THF	1 mM	1.7579 mL	8.7894 mL	17.5787 mL	43.9468 mL
THF	5 mM	0.3516 mL	1.7579 mL	3.5157 mL	8.7894 mL
	10 mM	0.1758 mL	0.8789 mL	1.7579 mL	4.3947 mL
	15 mM	0.1172 mL	0.5860 mL	1.1719 mL	2.9298 mL

Zeaxanthin Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zeaxanthin144-68-3Endogenous MetabolitecarotenoideyeantioxidantmaculalipophilictissuescholesterolInhibitorinhibitorinhibit

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Zeaxanthin

Customer Review

Zeaxanthin Related Antibodies

2 Publications Citing Use of MCE Zeaxanthin

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Zeaxanthin Related Antibodies

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Complete Stock Solution Preparation Table

Zeaxanthin Related Classifications

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