1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Vitamin D Related/Nuclear Receptor
  3. PPAR
  4. PPARγ Isoform
  5. PPARγ Antagonist

PPARγ Antagonist

PPARγ Antagonists (6):

Cat. No. Product Name Effect Purity
  • HY-16578
    Antagonist 99.87%
    GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
  • HY-13202
    Antagonist 99.98%
    T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.
  • HY-114263
    Antagonist 99.20%
    NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively.
  • HY-148351
    Antagonist 98.07%
    BAY-0069 is a potent and selective PPARγ inverse agonist with an IC50 value of 6.3 nM and 24 nM for human PPARγ and mouse PPARγ.
  • HY-128487
    H-​Trp-​Glu-​OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM.
  • HY-148352
    Antagonist 98.83%
    BAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC50 of 0.17 nM.