1-O-Hexadecylglycerol
Based on 1 Customer Validation
1-O-Hexadecylglycerol can up-regulate PPAR-γ expression, inhibit pGE2, and exhibit anti-inflammatory properties. 1-O-Hexadecylglycerol is effective in oral administration.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 6145-69-3
- Formula: C19H40O3
- Molecular Weight:316.53
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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HY-L004
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Immunology/Inflammation Compound Library
HY-L007
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Metabolism/Protease Compound Library
HY-L012
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Anti-Aging Compound Library
HY-L034
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Orally Active Compound Library
HY-L061
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Anti-Obesity Compound Library
HY-L087
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Transcription Factor-Targeted Library
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Lipid Metabolism Compound Library
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Nuclear Receptor Compound Library
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Metabolic Enzyme Compound Library
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Multi-Target Compound Library
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MCE Bioactive Compound Library
HY-L001V
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
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PPAR-γ |
Chemical Information
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CAS No. 6145-69-3
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Appearance Solid
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Molecular Weight 316.53
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Formula C19H40O3
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Color White to off-white
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SMILES
OC(CO)COCCCCCCCCCCCCCCCC
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Synonyms
1-O-HDG; HXDG
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 200 mg/mL (631.85 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Yokota M, et al. Chimyl Alcohol Suppresses PGE2 Synthesis by Human Epidermal Keratinocytes through the Activation of PPAR-γ. J Oleo Sci. 2018 Apr 1;67(4):455-462. [Content Brief]
[2]. BLOMSTRAND R et al Absorption of chimyl alcohol in man. Proc Soc Exp Biol Med. 1959 Apr;100(4):802-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1593 mL | 15.7963 mL | 31.5926 mL | 78.9815 mL |
| 5 mM | 0.6319 mL | 3.1593 mL | 6.3185 mL | 15.7963 mL | |
| 10 mM | 0.3159 mL | 1.5796 mL | 3.1593 mL | 7.8981 mL | |
| 15 mM | 0.2106 mL | 1.0531 mL | 2.1062 mL | 5.2654 mL | |
| 20 mM | 0.1580 mL | 0.7898 mL | 1.5796 mL | 3.9491 mL | |
| 25 mM | 0.1264 mL | 0.6319 mL | 1.2637 mL | 3.1593 mL | |
| 30 mM | 0.1053 mL | 0.5265 mL | 1.0531 mL | 2.6327 mL | |
| 40 mM | 0.0790 mL | 0.3949 mL | 0.7898 mL | 1.9745 mL | |
| 50 mM | 0.0632 mL | 0.3159 mL | 0.6319 mL | 1.5796 mL | |
| 60 mM | 0.0527 mL | 0.2633 mL | 0.5265 mL | 1.3164 mL | |
| 80 mM | 0.0395 mL | 0.1975 mL | 0.3949 mL | 0.9873 mL | |
| 100 mM | 0.0316 mL | 0.1580 mL | 0.3159 mL | 0.7898 mL |
1-O-Hexadecylglycerol Related Classifications
HY-W011309 Related Classifications
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