22978-25-2
22978-25-2
Chemical Structure
GW9662
- CAS No.: 22978-25-2
- Formula:C13H9ClN2O3
- Molecular Weight:276.68
IUPAC Name: 2-chloro-5-nitro-N-phenylbenzamide
InChIKey: DNTSIBUQMRRYIU-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC=C1)C2=CC([N+]([O-])=O)=CC=C2Cl
Biological Activity: GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
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GW9662 | 99.98% | GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively. | ||||||||||||||||||||
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GW9662 (Standard) | 99.92% | GW9662 (Standard) is the analytical standard of GW9662. This product is intended for research and analytical applications. GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively. | ||||||||||||||||||||
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GW9662-d5 | GW9662-d5 is the deuterium labeled GW9662. GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-13202T0070907 -
Similarity Score 0.85
HY-W649594NR2F6 modulator-2 -
Similarity Score 0.75
HY-W5206572-Amino-5-nitro-N-(o-tolyl)benzamide -
Similarity Score 0.72
HY-W0115962-Amino-2'-chloro-5-nitrobenzophenone -
Similarity Score 0.71
HY-B21202-Amino-5-nitrobenzophenone -
Similarity Score 0.69
HY-118639CP-74006 -
Similarity Score 0.69
HY-1269442-Aminobenzanilide -
Similarity Score 0.68
HY-W150426Naphthol AS-BS -
Similarity Score 0.68
HY-108422Benodanil -
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