1. Autophagy Metabolic Enzyme/Protease
  2. Autophagy HMG-CoA Reductase (HMGCR)
  3. Pravastatin

Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Pravastatin sodium) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Pravastatin Chemical Structure

Pravastatin Chemical Structure

CAS No. : 81093-37-0

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Description

Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM[1].

IC50 & Target

HMG-CoA reductase[1]

In Vitro

Pravastatin (CS-514) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

424.53

Formula

C23H36O7

CAS No.
SMILES

O[C@@H](C[C@@H](O)CC(O)=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@@H](O)C2)([H])[C@H]2OC([C@@H](C)CC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pravastatin
Cat. No.:
HY-B0165
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