1. Metabolic Enzyme/Protease
    Autophagy
  2. HMG-CoA Reductase (HMGCR)
    Autophagy
  3. Pravastatin sodium

Pravastatin sodium (Synonyms: CS-514 sodium)

Cat. No.: HY-B0165A Purity: 99.32%
Handling Instructions

Pravastatin (sodium) (CS-514 (sodium)) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

For research use only. We do not sell to patients.

Pravastatin sodium Chemical Structure

Pravastatin sodium Chemical Structure

CAS No. : 81131-70-6

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
50 mg USD 77 In-stock
Estimated Time of Arrival: December 31
100 mg USD 120 In-stock
Estimated Time of Arrival: December 31
200 mg USD 156 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Pravastatin (sodium) (CS-514 (sodium)) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

IC50 & Target

HMG-CoA reductase[1].

In Vitro

Pravastatin (CS-514) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease[1].

Clinical Trial
Molecular Weight

446.51

Formula

C₂₃H₃₅NaO₇

CAS No.

81131-70-6

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (223.96 mM; Need ultrasonic)

H2O : ≥ 50 mg/mL (111.98 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2396 mL 11.1980 mL 22.3959 mL
5 mM 0.4479 mL 2.2396 mL 4.4792 mL
10 mM 0.2240 mL 1.1198 mL 2.2396 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.32%

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Pravastatin sodium
Cat. No.:
HY-B0165A
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